1 / 15

Management of Ependymomas

Management of Ependymomas. George Jallo Division of Pediatric Neurosurgery Johns Hopkins University. Differential Diagnosis Ventricle Tumors. Ependymoma Astrocytoma Subependymoma Epidermoid Medulloblastoma Choroid Plexus tumor. Posterior Fossa Tumors: Clinical Features.

mili
Download Presentation

Management of Ependymomas

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Management of Ependymomas George Jallo Division of Pediatric Neurosurgery Johns Hopkins University

  2. Differential Diagnosis Ventricle Tumors EpendymomaAstrocytoma SubependymomaEpidermoid Medulloblastoma Choroid Plexus tumor

  3. Posterior Fossa Tumors: Clinical Features • 5-6% of intracranial tumors • 69% occur in children • 3rd most common pediatric brain tumor • 58% present in fourth ventricle

  4. Pathology: Ependymomas

  5. Imaging

  6. Imaging of Ependymomas

  7. Treatment • Goal: Gross total resection • Recurrence is common • Adjuvant therapy • Radiotherapy beneficial • Chemotherapy: no proven benefit

  8. Ependymomas: Survival vs. Age Spagnoli, P. et al. “Combined Treatment of Fourth Ventricular Ependymomas: Report of 26 cases.” Surgical Neurology. 2000; 54 (1): 19-26.

  9. Survival Rate vs. Radical Resection Subtotal Spagnoli, P. et al. “Combined Treatment of Fourth Ventricular Ependymomas: Report of 26 cases.” Surgical Neurology. 2000; 54 (1): 19-26.

  10. Microanatomical Location vs. Resection of Tumor Subtotal Spagnoli, P. et al. “Combined Treatment of Fourth Ventricular Ependymomas: Report of 26 cases.” Surgical Neurology. 2000; 54 (1): 19-26.

  11. Microanatomical Location vs. Survival Rate Spagnoli, P. et al. “Combined Treatment of Fourth Ventricular Ependymomas: Report of 26 cases.” Surgical Neurology. 2000; 54 (1): 19-26.

  12. Rogers, L et al. “Is Gross-Total Resection Sufficient for Posterior Fossa Ependymomas?” Journal of Neurosurgery. 2005 Apr; 102(4): 629-636.

  13. Local Control vs. Treatment Rogers, L et al. “Is Gross-Total Resection Sufficient for Posterior Fossa Ependymomas?” Journal of Neurosurgery. 2005 Apr; 102(4): 629-636.

  14. Prognostic Factors Rogers, L et al. “Is Gross-Total Resection Sufficient for Posterior Fossa Ependymomas?” Journal of Neurosurgery. 2005 Apr; 102(4): 629-636.

  15. Conclusions • Surgical resection is goal • Adjuvant radiotherapy is helpful for residual disease if not resectable • Role of chemotherapy still not determined

More Related