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Self-experimentation in medicine. Notable examples of medical self-experimentation ABO blood group Cardiac catheterization Thrombocytopenia Helicobacter pylori Cholera Effects of forces on the body Psychoactive drugs Yellow fever Alcohol Heavy water Neural implant Skin transplant
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Notable examples of medical self-experimentation • ABO blood group • Cardiac catheterization • Thrombocytopenia • Helicobacter pylori • Cholera • Effects of forces on the body • Psychoactive drugs • Yellow fever • Alcohol • Heavy water • Neural implant • Skin transplant • Snake bite • Weight balance • Asthma • Bartonellosis
John Hunter 1728-1793 • one of the most distinguished scientists and surgeons of his day • self-inoculation with gonorrhea and syphilis • Jekyll & Hyde Charles Byrne (8’ 1”)
William Harvey • Discoveries • Disproved Galen that blood not made from the liver • Heart is a pump not a suction device • Showed closed circuit circulation • Showed existence of valves in veins 1578-1657
Max von Pettenkofer 1818-1901 drank choleric bacteria. • miasma, noxious air associated with the air from rotting or fecal material • Contagionists, disease caused by something that was catching, like smallpox or syphilis
Werner Forssmann 1930’s Cardiac catheterization • Won the Nobel Prize for medicine • Hospital administrators removed him from his position owing to his unorthodox methods.
Barry Marshall Ulcer Helicobacter pylori
Tim Friede Snakebite & anti-venom Black mamba http://timfriede.com/
Craig Venter Celera Genomics
Disturbing Experiments • Inter-species breeding (ape-man, Ilya Ivanovich Ivanov, Guinea, 1927) = +
Disturbing Experiments • Two-headed dog (Vladimir Petrovich Demikhov, 1950s, Russia) http://www.youtube.com/watch?v=uvZThr3POlQ