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Department of Nuclear Medicine & PET-CT

Department of Nuclear Medicine & PET-CT. Radionuclides for Human wellbeing. Facilities Available. PET-CT (Siemens True point Biograph mCT-40 slice CT)- India’s first Ultra HD PET-CT. SPECT Gamma Camera (GE Millennium MG)

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Department of Nuclear Medicine & PET-CT

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  1. Department of Nuclear Medicine & PET-CT Radionuclides for Human wellbeing

  2. Facilities Available • PET-CT (Siemens True point Biograph mCT-40 slice CT)- India’s first Ultra HD PET-CT. • SPECT Gamma Camera (GE Millennium MG) • Radioiodine Therapy Ward for treatment of Thyroid Cancer patients.

  3. PET-CT POSITRON EMISSION TOMOGRAPHY MOLECULAR IMAGING IN COMPREHENSIVE CANCER CARE

  4. MINIMUM DOSE MAXIMUM SPEED INDIA’S FIRST ULTRA HD PET-CT

  5. PET - CT ONE STOP SHOP FOR CANCER CARE ANATOMETABOLIC DIAGNOSIS EARLY DETECTION DEFINES THE SEVERITY & EXTENT SURVEYS ENTIRE BODY IN A SINGLE STUDY

  6. PET-CTAnato-metabolic imaging CT SCAN PET SCAN FUSION

  7. PET – CT Applications in Oncology • Diagnosis • Staging • Treatment Response • Restaging • Radiotherapy Planning • Guiding Biopsy in a wide range of Cancers.

  8. Breast Cancer Detection / Staging

  9. Very early prediction of responseto chemotherapy & change of chemotherapy

  10. Carcinoma lung - Treatment response monitoring Before Chemotherapy After Chemotherapy Metabolic response

  11. BRAIN TUMOR RECURRENCE

  12. DIAGNOSING UNKNOWN CANCER Liver lesions on CT scan? Metastases or Hepatoma PET CT DIAGNSOED COLONIC CANCER WITH LIVER SECONDARIES

  13. PET DIRECTED BIOPSY Minimizing sampling error

  14. Treatment planning: Better Tumor Definition • Cut and • Paste the • RT dose • IMRT • IGRT • Give max • dose to tumor • where it is • proliferating • more Dose painting

  15. NONONCOLOGICAL APPLICATIONS OF PET - CT Cardiology: • Assesment of Myocardial viability Neurology: • Epilepsy • Neurodegenerative disorders • Anxiety & depressive disorders.

  16. CARDIAC PET-CT • ASSESMENT OF VIABILITY

  17. INFECTION LOCALIZATION / EXTENT

  18. Alzheimer’s Disease • EARLY DIAGNOSIS OF MILD COGNITIVE IMPAIREMENT • DIFFERENTIATES VARIOUS CAUSES OF MEMORY LOSS

  19. Multiinfarct dementia

  20. SEIZURE FOCUS LOCALIZATION A case of Left MTS

  21. Nuclear Medicine & PET-CT Gamma Camera

  22. Dual Head Gamma Camera (Millennium MG)

  23. Dual Head Gamma Camera (Millennium MG) • Radiopharmaceuticals are organ specific chemical compounds combined with radionuclides. • These radiopharmaceuticals, once administered to the patient, localize to specific organs or cellular receptors which allows us to image the extent of a disease-process in the body, based on the cellular function (Physiology), rather than relying on physical changes in the tissue anatomy.

  24. Application Functional/Physiological imaging of various Organs/Organ systems

  25. BONE SCAN • Highly sensitive • Surveys entire body in a single study • Diagnoses the lesion earlier than radiograph

  26. BONE SCAN EARLY Diagnosis of bone secondaries in a cancer patient

  27. THYROID SCAN • Provides the Uptake Function of Thyroid Gland • Detectes Nonfunctioning Nodules (30% of Which Could be Cancerous ) • Differentiates Hyperthyroidism Causes

  28. Thyroid Scan Graves’ Disease • Curable with Radioiodine Therapy

  29. Patient Presented with Thyroid Swelling • Thyroid Scan Shows Nonfuntioning Nodule • Biopsy Revealed Thyroid Cancer

  30. Complete Cure for Thyroid Cancer at early stage (Papillary & Follicular Varieties) is Possible with • Surgical Removal of Thyroid Gland with Neck Lymphnode Dissection Followed By • High Dose Radioiodine Therapy Comprehensive Cancer Care Under One Roof

  31. RENAL SCAN • FUNCTIONAL IMAGING OF RENAL SYSTEM • GIVES ACCURATE FUNCTIONAL STATUS ( GFR) • RULES OUT URINE OUTFLOW OBSTRUCTION IN THE RENAL SYSTEM • DIAGNOSE INFECTION AT THE EARLIEST • EARLY DETECTION OF KIDNEY TRNASPLANT COMPLICATIONS • EVALUATION OF ACCELERATED HYPERTENSION (CAPTOPRIL RENOGRAM)

  32. DTPA Renal Scan Left PUJ Obstruction

  33. PYELONEPHRITIS INFECTED SCARRED KIDNEYS

  34. MYOCARDIAL PERFUSION SCAN Noninvasive Scan Early Diagnosis of Cardiac Problems Related to Blood Circulation Preoperative Assemment of Perfusion / Functional Stauts of Heart

  35. Myocardial Perfusion ScanNormal Scan

  36. Infero-Lateral wall Ischaemia

  37. BRAIN SCAN • Accurate Localisation of Foci in Refractory Epilepsy Patients • Neurodegenerative Disorders • Evaluation of Movement Disorders • Cerebrovascular Disorders.

  38. ICTAL SPECT • Seizure focus origin in right temporal lobe • Highly sensitive

  39. Cerebrovascular Disease

  40. Lung Scan Pulmonary Embolism • NON INVASIVE • GIVES PERFUSION AT SUB SEGMENTAL LEVEL • EASY FOLLOW UP

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