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Principles and Patterns of Inheritance

Principles and Patterns of Inheritance. The History of Genetics. I.History of Genetics Genetics - the scientific study of inheritance The domestication of dogs is one of the earliest human experiences with genetics. Millions of years ago there were no dogs.

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Principles and Patterns of Inheritance

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  1. Principles and Patterns of Inheritance

  2. The History of Genetics • I.History of Genetics • Genetics - the scientific study of inheritance • The domestication of dogs is one of the earliest human experiences with genetics. • Millions of years ago there were no dogs. • Today’s domestic dogs are descended from a wolf ancestors

  3. The History of Genetics • Ancient people selected traits to be passed from generation to generation. • Trait - a characteristic that can be passed from parent to offspring

  4. The History of Genetics • It has not always been understood how traits are passed from parent to offspring. • For many centuries scientists believed that traits were blended in offspring, they would later learn that this idea was incorrect.

  5. The History of Genetics • Review: • during cell division chromosomes are replicated and distributed to daughter cells during meiosis. • The traits that are passed from parents to offspring are in these chromosomes

  6. Gregor Mendel • II.Gregor Mendel • Clues to understanding inheritance came from an Austrian monk, Gregor Mendel, in the 1860’s.

  7. Gregor Mendel • He used pea plants to study how traits were passed from one generation to the next. • Mendel gathered detailed information on more than 20,000 pea plants over an eight year period. • He applied mathematics and statistics to his findings and found that they did not support the blending hypothesis.

  8. Mendel's Experiments • III. Mendel’s Experiments • Mendel chose to work with the pea plant for several reasons: 1. the structure of the pea plant- the pea flower petals make it very easy for the pollen from the anther from a plant to fertilize it’s own pistil.

  9. Mendel's Experiments • This produced a purebred offspring. purebred offspring - receives the same genetic traits from both parents

  10. Mendel's Experiments • Mendel was also able to transfer pollen from one plant to another by hand. This produced a hybrid. • hybrid offspring - receives different forms of a genetic trait from each parent

  11. Mendel's Experiments 2. Presence of distinctive traits Mendel studied several traits Each of the traits had two distinct forms ex. pea pods are either yellow or green, there is no intermediate

  12. Mendel's Experiments 3. Rapid reproduction cycle This allowed Mendel to repeat his experiments many times to test his results

  13. Mendel's Observations • IV. Mendel’s Observations Mendel began his experiments using two different groups of inbred plants. He called this the parents (or P) generation. yellow pea x green pea

  14. Mendel's Observations • He called the offspring of that mating the first filial generation or F1 generation. 100%yellow pea plants • Mendel let the F1 plants self fertilize to produce the F2 generation. 75% of the F2offpsring produced were yellow while 25% were green.(3:1 ratio)

  15. Mendel's Observations

  16. Mendel's Conclusions • V. Mendel’s Conclusions • Mendel’s experiments showed that the blending hypothesis was wrong. • Mendel hypothesized that each trait is controlled by a distinct “factor”

  17. Mendel's Conclusions • We now know that Mendel’s “factors” are genes. • Gene - a section of a chromosome that codes for a particular trait.

  18. Mendel's Conclusions • Alleles - different forms of a gene (ex. yellow, green in peas) Alleles are represented by letters ex. Y=yellow, y= green

  19. Mendel's Conclusions • dominant allele - form of the gene that is expressed fully when two different alleles are present • recessive allele - form of the gene not expressed when two different alleles are present.

  20. Mendel's Conclusions • Letters are used to represent alleles: the dominant traits is represented by an uppercase letter ex.Y • the recessive allele is represented by a lower case letter ex.y

  21. Mendel's Conclusions • Mendel published his work in 1866, his work went unrecognized for 37 years. In 1903, Walter S.Sutton used a microscope and observed that chromosomes behaved like Mendel’s factors.

  22. genes Chromosome

  23. Genes Affect Traits • VI. Genes Affect Traits • GENOTYPE - the genetic make up of an organism. The genotype includes both genes in a pair of homologous chromosomes. • genotype of purebred yellow peas is YY • genotype of hybrid yellow peas is Yy • genotype of green peas_______

  24. Genes Affect Traits • PHENOTYPE - the outward expression of a trait • phenotype for F1 generation of peas is yellow Green seeds Yellow seeds

  25. Genes Affect Traits • If the two alleles of the gene are the same they are called homozygous. ex. YY, yy • If the two alleles of the gene are different they are called heterozygous ex.Yy

  26. Mendel's Laws • VII. Mendel’s Laws • The basic rules of inheritance are called Mendel’s Laws • Law of Segregation- each pair of genes segregates and ends up in gametes during meiosis • half an organisms gametes contain one chromosome from a homologous pair, the other half contain the other chromosome

  27. Mendel's Laws • Law of Independent Assortment - gene pairs separate into gametes randomly and independently of one another.

  28. Mendel's Laws • Law of Dominance - recessive allele is expressed only when the organism has no copy of the corresponding dominant allele

  29. Mendel's Laws

  30. Genetic Interactions

  31. IX. Genetic Interactions Complete dominance – the dominant allele masks the recessive allele Genetic Interactions Recessive trait : Sugary kernels shown only when no dominant allele is present Dominant trait: Yellow kernels

  32. Genetic Interactions • incomplete dominance - when two different alleles for the same trait combine the offspring is an intermediate ex.red snap dragon x white snap dragon = pink snap dragon

  33. Genetic Interactions • codominance - both alleles in the heterozygote express themselves fully ex. blood type

  34. Genetic Interactions • Polygenic Traits - traits affected by more than one gene. ex. eye color, skin color

  35. Probability • X. Probability • fractions, percentages, or ratios used to predict the likelihood of an outcome, you are measuring probability. • When you flip a coin, you can get either heads or tails The probability of getting heads is 1/2, 50%, 1:1 • Scientists can use probability to predict the outcome of breeding experiments.

  36. Probability

  37. The End

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