1 / 26

Histology of cartilage

Histology of cartilage. Introduction. Modified (solid type) of connective tissue. Forms the skeletal basis of some parts of the body. Avascular E.g. Auricle of the ear, lower part of the nose. Components. Cells. Matrix. Chondrocytes. Fibers Collagen OR Elastic fibers

mitchellmartha
Download Presentation

Histology of cartilage

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Histology of cartilage

  2. Introduction • Modified (solid type) of connectivetissue. • Forms the skeletal basis of some parts of the body. • Avascular • E.g. Auricle of the ear, lower part of the nose. Histology of cartilage

  3. Components Cells Matrix Chondrocytes • Fibers • Collagen OR • Elastic fibers • Ground substance • Tissue fluid • GAG & proteoglycans Histology of cartilage

  4. Chondrocytes • Derived - chondroblast • Chondroblast - mesenchymal cell • Seen in spaces- lacunae Histology of cartilage

  5. 3 types of cartilage • Hyaline cartilage • Elastic cartilage • Fibrocartilage Histology of cartilage

  6. Histology of cartilage

  7. Matrix (fibers + ground substances) • Type II collagen fibers • Proteoglycans, Hyaluronic acid • Capsule or territorial matrix • Interterritorial matrix • Lacunae(tiny spaces in the matrix) • Isogenous cell nest / CELL NESTS (offspring of a common parent cell). Histology of cartilage

  8. Seen under microscope Histology of cartilage

  9. Hyaline cartilage Chondrogenic layer Fibrous layer Perichondrium Chondroblasts Cell nest Matrix Chondrocyte in lacuna

  10. Hyaline cartilage- magnified Terretorial matrix Interterretorial matrix Chondrocyte in lacuna Cell nest

  11. Distribution • Costal cartilage • Articular cartilage • Thyroid, cricoid, arytenoid • Tracheal rings • Part of nasal septum • Epiphyseal plate Histology of cartilage

  12. Elastic cartilage (yellow fibrocartilage) • Greater flexibility. • Ground substance contains abundance of branching and anastomosing elastic fibres. • No isogenous cell nests. • Chondrocytes are found in single or in small groups. Histology of cartilage

  13. Elastic cartilage Histology of cartilage

  14. Elastic cartilage (microscopic view) Histology of cartilage

  15. Elastic cartilage Fibrous layer Chondrogenic layer Perichondrium Chondroblast Matrix with elastic fibers Chondrocyte in the lacuna

  16. Distribution • Auricle & lateral part of the external acoustic meatus. • Medial part of auditory tube. Histology of cartilage

  17. Epiglottis, corniculate, cuneiform, apical part of arytenoid. Histology of cartilage

  18. White fibrocartilage • It is intermediate between Dense connective tissue and hyaline cartilage (tensile strength) • Chondrocytes are found in singles or in rows with bundles of collagen with little matrix. • No perichondrium. • Bundles of collagen (type1) Histology of cartilage

  19. White fibrocartilage Histology of cartilage

  20. White fibrocartilage (microscopic view) Histology of cartilage

  21. White-fibro cartilage Chondrocyte Matrix

  22. Distribution • Secondary cartilaginous joints • intervertebral discs, • pubic symphysis. Histology of cartilage

  23. Articular discs Histology of cartilage

  24. Menisci of the knee joint Histology of cartilage

  25. Growth of Cartilage • Interstitial Growth ?? • Appositional Growth?? Histology of cartilage

  26. Histology of cartilage

More Related