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Università degli Studi di Messina UOC di Cardiochirurgia Azienda Ospedaliera Universitaria Policlinico “G. Martino” dir. Prof. Roberto Gaeta. PROTESI VALVOLARI CARDIACHE - corso integrato malattie apparato cardiovascolare e respiratorio -. Prof R Gaeta Chirurgia Cardiaca (SSD Med 23).
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Università degli Studi di MessinaUOC di CardiochirurgiaAzienda Ospedaliera Universitaria Policlinico “G. Martino”dir. Prof. Roberto Gaeta PROTESI VALVOLARI CARDIACHE - corso integrato malattie apparato cardiovascolare e respiratorio - Prof R Gaeta Chirurgia Cardiaca (SSD Med 23)
PROTESI VALVOLARI CARDIACHE • ARTIFICIALI • BIOPROTESI PALLA DISCO BIDISCO AUTOLOGHE OMOLOGHE ETEROLOGHE
PROTESI VALVOLARI CARDIACHE ARTIFICIALI STARR-EDWARDS MAGOVERN SMELOFF-CUTTER PALLA
Braunwald Polyurethane mitral valve. First mitral valve replacement on March 11, 1960. Teflon chordae brought through the ventricular muscle and secured outside the heart Kay Mitral Valve. Teflon mitral valve prosthesis with artificial chordae. Implanted 1959 Original Starr-Edwards Mitral Valve. Lucite cage. Silastic rubber ball occluder. Implanted 1960. Harken double cage ball valve. Implanted in 1960
PROTESI VALVOLARI CARDIACHE ARTIFICIALI BEALL BJORK SHILEY SORIN MEDTRONIC HALL LILLEHEI KASTER MONODISCO
PROTESI VALVOLARI CARDIACHE ARTIFICIALI ST. JUDE CARBOMEDICS DUROMEDICS SORIN BIDISCO
Flow characteristics • ball/cage < tilting dic < bileaflet • Thrombogenic potential • ball/cage > tilting disc > bileaflet • Aortic < Mitral < both
PROTESI VALVOLARI CARDIACHE • ARTIFICIALI • BIOPROTESI PALLA DISCO BIDISCO AUTOLOGHE OMOLOGHE ETEROLOGHE
PROTESI VALVOLARI CARDIACHE BIOPROTESI PERICARDICHE FASCIA LATA V. POLMONARE (Intervento di ROSS) AUTOLOGHE
PROTESI VALVOLARI CARDIACHE • STENTED • PORCINE • PERICARDICHE • STENTLESS • PORCINE • BOVINE • PERICARDICHE BIOPROTESI AUOTGRAFT OMOGRAFT
Pulmonary Autograft (Ross Procedure- 1967) • Advantages • Viable tissue, excellent hemodynamics • Near 0% thromboembolism, growth potential • Non-antigenic • Pulmonary valve equal in strength as aortic valve • Disadvantage • Creating 2-way valve pathology from single valve disease • Results • Freedom from re-operation 81% at 8 years • 5-10% annular dilatation and regurgitation • Pulmonary homograft deterioration • Technique • Root replacement preferred • Tailoring of aortic/pulmonary size mismatch • Bolstering ring with Dacron strip • Long-term follow-up still accruing
PROTESI VALVOLARI CARDIACHE BIOPROTESI OMOLOGHE HOMOGRAFT (cadavere)
PROTESI VALVOLARI CARDIACHE BIOPROTESI BOVINE C-E HANCOCK MITROFLOW XENOGRAFT
PROTESI VALVOLARI CARDIACHE ARTIFICIALI • ANTICOAGULAZIONE • LUNGA DURATA • RUMORE
Anticoagulation Management (Machanical Prosthesis) • TIA is most common event • Standardization of coagulation management (INR) • Narrow therapeutic range: balance between thrombolic and bleeding risk • ACCP recommendations: INR 2.5-3.5 • Aortic: 2.5-3.0 • Mitral: 3.0-3.5 • Both: 3.5-4.0 • Appropriate use of antiplatelet therapy
PROTESI VALVOLARI CARDIACHE BIOLOGICHE • NO ANTICOAGULAZIONE • DURATA MEDIA (10-12 anni) • SILENZIOSE
PROTESI VALVOLARI CARDIACHE • TROMBOEMBOLIA • INFEZIONI • LEAK
The Perfect Valve • Excellent hemodynamics • Non-thrombogenic • Durable • Unrestricted availability • Easily implantable • Silent function • Low cost
Anatomy and Pathology 1. Crucial to understand the anatomy of the mitral valve in order or perform valve repair/surgery 2. Mitral valve is composed of five separate components: a. valvular leaflets b. annulus c. chordae tendinae d. papillary muscles e. left ventricular wall
Pathology • Rheumatic Disease • Myxomatous Degeneration • Ischemic Valvulopaty • Endocarditis