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Dermatological Disorders: Pemphigus, Lichen Planus, and Erythema Multiforme

Learn about classification, manifestations, and treatments of various vesiculobullous and mucocutaneous diseases such as Pemphigus, Lichen Planus, and Erythema Multiforme. Explore detailed insights into their introduction, pathogenesis, clinical features, diagnostic tests, histopathology, differential diagnosis, and recommended treatments.

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Dermatological Disorders: Pemphigus, Lichen Planus, and Erythema Multiforme

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  1. Diseases of skin DrMaji Jose

  2. Essay 7 marks • Classify vesiculobullous diseases / enumerate mucocutaneous diseases. Discuss in detail Pemphigus ( 2+5= 7 marks) Ans: Classification/ Listing of lesions Pemphigus- Introduction, Pathogenesis, C/F, Cytological test, H/P, D/D, Treatment

  3. Essay 7 marks • Classify vesiculobullous diseases / enumerate mucocutaneous diseases. Discuss in detail Lichen planus ( 2+5= 7 marks) Ans: Classification/ Listing of lesions Lichen planus- Introduction, Pathogenesis, C/F,O/M, H/P, Treatment

  4. Essay 7 marks • Classify vesiculobullous diseases / enumerate mucocutaneous diseases. Discuss in detail Erythema multiforme ( 2+5= 7 marks) Ans: Classification/ Listing of lesions Erythema multiforme- Introduction, Pathogenesis, C/F with description of different types, H/P, D/D, Treatment

  5. Short essays5 marks • Hereditary ectodermal dysplasia • O/M of Lichen Planus • Pathogenesis of lichen planus • H/P of Lichen planus • C/F & H/P of pemphigus • Steven Johnson syndrome • White sponge nevus • Cicatricialpemphigoid/ benign mucous membrane pemphigoid • Bullous membrane pemphigoid • Crest syndrome

  6. Short notes2marks • Wickham’s striae • Auspitz’s sign • Monro abscess • Nikolski sign • Tzanck test • Bull’s eye lesion/ target lesion • Butterfly rashes • ‘Rubber man” • Gorlinsign • GoltzGorlinsyndrome • LE cell test

  7. Objective type questions1mark • Hereditary ectodermal dysplasia is characterized by hypohidrosis, hypotrichosis and hypodontia • Oligodontia with Conical shape of teeth present are characteristic of Hereditary ectodermal dysplasia • Steven Johnson syndrome is severe form of erythema multiforme • Bull’s eye lesion / target lesion is characteristic of erythema multiforme • Intraepithelial/suprabasillar split is characteristic of pemphigus

  8. When pemphigus like lesions occur in patients suffering from lymphoreticular malignancy is referred to as para neoplastic pemphigus • Dilapidated brick wall appearance is characteristic of Hailey Hailey disease • Vesiculobullous lesions with extensive scarring are characteristic of cicarticialpemphigoid • Goltz – Gorlin syndrome is another name for focal dermal hypoplasia syndrome • LE cell test is done to diagnose lupus erythematosis • Butterfly rashes are characteristic of lupus erythematosis

  9. Gorlinsign is characteristic of Ehler’sDanlos syndrome • Corps, ronds and grains are characteristic of Darier’sdisease/ keratosis follicularis • Wickham’s striae is characteristic of Lichen planus • Commonest clinical type of lichen planus is reticular type • Auspitz’s sign is characteristic of psoriasis • Monroabscess is characteristic of psoriasis • Symmetric widening of periodontal ligament involving multiple teeth is characteristic of systemic sclerosis

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