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The Real Deal on Marijuana

The Real Deal on Marijuana. Cannabis. Pot, herb, weed, grass, widow, ganja, hash, dank, mota/moto, hierba, pasto, etc. STRUCTURE OF THE ACTIVE REAGENT. THC Concentration is Different in Various Preparations of Marijuana. “Ordinary” marijuana ~3%

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The Real Deal on Marijuana

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  1. The Real Deal on Marijuana

  2. Cannabis • Pot, herb, weed, grass, widow, ganja, hash, dank, mota/moto, hierba, pasto, etc.

  3. STRUCTURE OF THE ACTIVE REAGENT

  4. THC Concentration is Different in Various Preparations of Marijuana • “Ordinary” marijuana ~3% • Sinsemilla (seedless female plant) -7.5% average, up to 24% • Hashish (cannabis buds)- 3.6% average, up to 28% • Hash oil (non-polar extract of marijuana or hashish)- 16% average, up to 43%

  5. Cell Biology: Marijuana is a drug that binds receptors on cell membranes marijuana Binding of the drug to the receptor causes changes within the cell receptor Structural changes Functional changes cell

  6. Effects of Smoking Cannabis • Euphoria followed by tiredness, passivity • Eye reddening (a hallmark) • Increased heart rate, dry mouth and eyes • Dizziness • Defects in short-term memory and cognition • Lung Disease • Hormone abnormalities (gynecomastia)

  7. Pathway Of Marijuana In The Body lips/mouth inhale marijuana lungs bloodstream brain other organs/ tissues heart

  8. Normal Lungs and Physiology Lungs are the site of gas exchange: oxygen enters blood and carbon dioxide leaves blood

  9. Marijuana Damages the Lungs • Marijuana contains tar, carbon monoxide, and • carcinogens that damage the lungs • Marijuana smoke contains 50 to 70% more toxic chemicals • than tobacco smoke • Marijuana use increases the risk of lung disease

  10. Diseased Lung Healthy Lung

  11. The Heart I Right side of heart pumps blood to the lung where it picks up oxygen; left side of heart pumps blood to the entire body.

  12. The Heart II

  13. Marijuana Harms Heart Function • Increases heart rate (tachycardia) • Vessels dilate (enlarge), disturbing heart function

  14. Marijuana Affects the Brain • Marijuana Acts On : • Cerebellum (coordination) • Basal ganglia (motor) • Hippocampus (memory)

  15. Marijuana Can Cause Brain Damage • Loss of short-term memory • Cognitive deficits • Apathy

  16. Altered hormone levels Enlarged breasts in males (gynecomastia) Hormone Problems are Associated with Marijuana Use

  17. Medical Marijuana • THC is available by prescription (Marinol) • Antiemetic (prevents vomiting) • Glaucoma • Muscle relaxant

  18. Contact Information Adolescent Counseling Services http://www.acs-teens.org 650-424-0852 or 650-424-9853 (Fax) 4000 Middlefield Road Rm FH, Palo Alto, CA 94303 Stanford Chapter of Student National Medical Association http://snma.stanford.edu Aileen Green aileen.green@stanford.edu ChaRandle Jordan csjordan@stanford.edu 650-497-9287

  19. References for Images http://www.oconeelaw.com/.../ marijuana/blunt.jpg http://www.netdoctor.co.uk/focus/heart/index.shtml cannabis.gif (chemical structure of THC)  http://www.toxlab.co.uk/cannabis.htm  man.gif (smoking stick figure)  http://www.colostate.edu/Depts/ NatSci/html/Major8.html  Lungs.jpg (schematic of lung)  http://www.alpha1.org.uk/COPD/ Illness/the_lung.htm  Lung Blood -air barrier copy W... (schematic of gas exchange in alveolus)  http://www.education.vetmed.vt.edu/.../EXAMPLES/ exgasbarrierdiag.htm  clean_lung_hr.jpg (healthy lung)  http://www.lungusa.org/learn/ art/clean_lung_hr.jpg  diseased_lung.jpg (diseased lung)  http://www.lungcancer.org/images/patients/ lungs/diseased_lung.jpg   bc47.jpg (sagittal brain)  http://www.cns.georgetown.edu/ medneuro/lab1/  brain.jpg (side view of head and brain)  http://www.bbc.co.uk/schools/ parents/

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