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Lipid Profiles & NSW

Lipid Profiles & NSW. LCDR Jim Mucciarone NSWG-2 16 July 2008. Study. Reviewed age, height, weight, total cholesterol, LDL, HDL and Triglycerides in 85 SEAL physicals conducted in CY 2007. Compared results with ATP-III standards for Cholesterol and LDL. Target for cholesterol < 200 mg/dl

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Lipid Profiles & NSW

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  1. Lipid Profiles &NSW LCDR Jim Mucciarone NSWG-2 16 July 2008

  2. Study • Reviewed age, height, weight, total cholesterol, LDL, HDL and Triglycerides in 85 SEAL physicals conducted in CY 2007. • Compared results with ATP-III standards for Cholesterol and LDL. • Target for cholesterol < 200 mg/dl • Target for LDL < 130 mg/dl

  3. Results • Avg Age: 32.83 (21-52) • Avg Cholesterol: 186.6 (108-312) • Avg LDL: 119.9 (70-221) • 22/85 (25.9%) Total Chol > 200 • 23/85 (27.1%) LDL > 130

  4. Biases • Age • 5 years AD, Retirement Physicals included • Medications • Excluded personnel known to be on meds • Fasting • Assumed patients fasted appropriately

  5. Significance • Increased serum cholesterol significantly associated with increased risk of death before age 50 (Klag, et al, NEJM, 1993) • Men < 39 y/o with serum cholesterol > 200 have increased overall mortality • > 240 = 2.10 to 3.63 RR of CHD or CVD death • Men < 39 y/o with chol < 200 = 3.8 to 8.7 years of life (Stamler, et al, JAMA, 2000) • “Grow the Force”

  6. Treatment • Therapeutic Lifestyle Changes • Reduce Sat Fats/Cholesterol • Reduce Body Weight • Increase stanols/sterols and fiber • Increase physical activity • Prefer to avoid statins • Lifelong medication • Assoc with muscle pain

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