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The Aging Eye and Circadian light: Brief Overview

The Aging Eye and Circadian light: Brief Overview. Thomas Hornick MD. . . Wikipedia, accessed 10/30/09 . Disruption of circadian rhythm. Poor performance/fatigue (Reinberg et al, 2007, Laposky et al 2008) Weight gain(Knutson et al, 2007) Breast cancer (Stevens et al 2001)

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The Aging Eye and Circadian light: Brief Overview

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  1. The Aging Eye and Circadian light:Brief Overview Thomas Hornick MD

  2. . Wikipedia, accessed 10/30/09

  3. Disruption of circadian rhythm • Poor performance/fatigue (Reinberg et al, 2007, Laposky et al 2008) • Weight gain(Knutson et al, 2007) • Breast cancer (Stevens et al 2001) • Other conditions

  4. Eye changes with age Corneal thickening reduces light Decreasing pupillary size. Decreasing ciliary contraction leads to presbyopia Lens opacifies, increases absorption of light, especially in shorter wavelengths Loss of retinal and optic nerve cells

  5. Aging and light • Older adults spend much of their time in muted indoor lighting. • 35 minutes/day of bright light exposure compared to approximately 58 minutes of bright light per day for middle-aged adults. (Sanchez 1993) • Reduced light exposure compounded due to physiologic changes • senile meiosis, cataract formation, and/or increased light absorption by the crystalline lens. (Charmin 2003) • Attenuation of light exposure by more than 80% in normal older adults relative to young adults.

  6. Spectral sensitivity of photopic, scotopic and circadian (melatonin suppression) photoreception Turner et al Br J Ophthalmol. 2008 November; 92(11): 1439–1444

  7. Circadian light transfer function Figueiro, et al. 2006

  8. Age related losses in retinal illumination Turner et al Br J Ophthalmol. 2008 November; 92(11): 1439–1444

  9. Wikipedia, accessed 5/2010

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