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Chapter 10. Muscle Tissue Lecture Outline. INTRODUCTION. Muscles: Make up 40-50% of the body weight Contribute to homeostasis The scientific study of muscles is known as myology. OVERVIEW OF MUSCLE TISSUE. There are 3 types of muscle tissue: Skeletal Cardiac Smooth.
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Chapter 10 Muscle Tissue Lecture Outline
INTRODUCTION • Muscles: • Make up 40-50% of the body weight • Contribute to homeostasis • The scientific study of muscles is known as myology.
OVERVIEW OF MUSCLE TISSUE • There are 3 types of muscle tissue: • Skeletal • Cardiac • Smooth Principles of Human Anatomy and Physiology, 11e
Skeletal Muscle Tissue • Skeletal muscle • Move the bones of the skeleton • Attaches to the bone or the skin • It is striated: alternating bands of dark and light • Voluntary control of contraction & relaxation Principles of Human Anatomy and Physiology, 11e
Cardiac Muscle Tissue • Cardiac muscle • Forms the wall of the heart • Striated in appearance • Control is involuntary • An internal pacemaker controls the heartbeat • This rhythm is called autorhymicity and is controlled by hormones, nerve impulses, and neurotransmitters Principles of Human Anatomy and Physiology, 11e
Smooth Muscle Tissue • Smooth muscle • Located in the walls of blood vessels, airways, and organs; also attached to hair follicles • Nonstriated in appearance (smooth) • Involuntary control • Propels food through your gastrointestinal tract Principles of Human Anatomy and Physiology, 11e
Functions of Muscle Tissue • Producing body movements • Stabilizing body positions • Regulating organ volumes • bands of smooth muscle called sphincters • Movement of substances within the body • blood, lymph, urine, air, food and fluids, sperm • Producing heat • involuntary contractions of skeletal muscle (shivering) produce heat through thermogenesis Principles of Human Anatomy and Physiology, 11e
Properties of Muscle Tissue • Excitability • respond to chemicals released from nerve cells • Conductivity • ability to propagate electrical signals over membrane • Contractility • ability to shorten and generate force • Extensibility • ability to be stretched without damaging the tissue • Elasticity • ability to return to original shape after being stretched Principles of Human Anatomy and Physiology, 11e
Muscles you need to know • Sternocleidomastoid (neck) • Trapezius (shoulder blade) Principles of Human Anatomy and Physiology, 11e
Muscles you need to know • Deltoid (shoulders) Pectoralis major (upper and lower chest) Principles of Human Anatomy and Physiology, 11e
Muscles you need to know • Biceps brachii • Brachialis • Brachioradialis • (humerus to radius) Principles of Human Anatomy and Physiology, 11e
Muscles you need to know • Latissimus dorsi (middle back) • Rectus abdominis (6-pack abs) • External oblique (side abs) Principles of Human Anatomy and Physiology, 11e
Muscles you need to know • The 4 muscles of the quadricep (thigh) • Vastus lateralis • Vastus intermedius • Vastus medialis • Rectus Femoris Principles of Human Anatomy and Physiology, 11e
Muscles you need to know • Triceps brachii (back of the arms) Principles of Human Anatomy and Physiology, 11e
Muscles you need to know • Infraspinatus (scapula) • Teres minor • (attaches scapula to humerus) • Teres major • (attaches humerus to ribs) Principles of Human Anatomy and Physiology, 11e
Muscles you need to know • Gluteus maximus (butt) • Semitendinosus (hamstring) • Biceps femoris (hamstring) Principles of Human Anatomy and Physiology, 11e
Muscle Poster Gallery Walk • Due Friday: gallery walk and note taking on: • Each group will create a poster that includes: • 2 detailed, colored drawings of your muscle group • Identify, label, and explain the function of 10 individual muscles • List one interesting fact/characteristic of your muscles • 1 (Erika): Face/Head (338-339) • 2 (Celine): Upper Arm/Shoulder (361, 364-5) • 3 (Jeffrey): Forearm, wrist, hands (368, 372-3, 376) • 4 (Rachelle): Vertebral column (381-2) • 5 (Jenny): Upper leg, femur (385-387) • 6 (Victoria): Lower leg, foot, toes (393-4, 397) • 7 (Marco): Thorax, abdomen (352, 354) • 8 (Ashley): The Whole Body (334-335) Principles of Human Anatomy and Physiology, 11e
SKELETAL MUSCLE TISSUE • Each skeletal muscle is a separate organ composed of cells called muscle fibers. Principles of Human Anatomy and Physiology, 11e
Connective Tissue Components • Connective tissue surrounds and protects muscular fibers (cells) • A tendon is a cord of dense connective tissue that attaches a muscle to the bone • An aponeurosisis a tendon that extends as a broad, flat layer. Principles of Human Anatomy and Physiology, 11e
Nerve and Blood Supply • Each skeletal muscle is supplied by a nerve, artery and two veins. • The nerve directs muscle movement and the artery supplies blood to the muscle. Principles of Human Anatomy and Physiology, 11e
Muscle Fibers • Muscle cells are long, cylindrical & multinucleated • A muscle fiber averages 4 inches long and can grow up to 12 inches. Principles of Human Anatomy and Physiology, 11e
Parts of a Muscle Cell • Skeletal muscle consists of fibers (cells) covered by a sarcolemma, the plasma membrane. • Transverse (T) tubules are tunnels that allow fluid to enter and exit cells
Parts of a Muscle Cell • Sarcoplasmis the muscle cell cytoplasm and contains a large amount of glycogen for energy production and myoglobin for oxygen storage. • Myofibrils allow the muscles to contract • Filaments are small structures that are also involved in muscle contraction
The Proteins of Muscle • Myofibrils (the part that contracts) are built of 3 kinds of protein • contractile proteins which generate force (myosin and actin) • Regulatory proteins which receive signals (troponin and tropomyosin) • Structural proteins which give elasticity to the muscle
Sliding Filament Mechanism Of Contraction • Thin and thick filament slide past each other • During muscle contraction, the filaments slide towards each other and the muscle is shortened • The muscle then relaxes and returns to normal length. Principles of Human Anatomy and Physiology, 11e
Neuromuscular Junction (NMJ) or Synapse • NMJ = neuromuscular junction: the space between a neuron and a skeletal muscle-sends nerve impulses into the muscle.
Muscle MetabolismProduction of ATP in Muscle Fibers • Muscle use ATP at a great rate when active • 3 sources of ATP production within muscle • creatine phosphate (synthesized from food) can power muscles for 15 seconds. • anaerobic cellular respiration (making ATP without oxygen, when exercising) can power muscles for 30 seconds. • aerobic cellular respiration (makes the most ATP) can power muscles for longer periods of time. Principles of Human Anatomy and Physiology, 11e
Muscle Fatigue • Inability to contract after prolonged activity • Why do your muscles get tired? • central fatigue is feeling of tiredness and a desire to stop (protective mechanism) • insufficient release of neurotransmitters from motor neurons • depletion of creatine phosphate • decline of Ca+2 within the sarcoplasm • insufficient oxygen or glycogen • buildup of lactic acid and ADP (anaerobic muscle activity) Principles of Human Anatomy and Physiology, 11e
Twitch contraction • A twitch contraction is a brief contraction of all the muscle fibers in a motor unit in response to a single action potential (one involuntary muscle movement). • A myogram is a graph of a twitch contraction
Myogram of a Twitch Contraction Principles of Human Anatomy and Physiology, 11e
Motor Unit Recruitment • Motor units in a whole muscle fire independently, at different times. • Produces smooth muscular contraction • not series of jerky movements Principles of Human Anatomy and Physiology, 11e
Isotonic and Isometric Contraction • Isotonic Contractions • Involves muscle movement • Isometric Contraction = no movement occurs • tension is generated but muscles do not move • maintaining posture & supports objects in a fixed position Principles of Human Anatomy and Physiology, 11e
Types of Muscle Fibers • Slow oxidative (slow-twitch) • red in color (lots of mitochondria, myoglobin & blood vessels) • prolonged, sustained contractions for maintaining posture • Oxidative-glycolytic (fast-twitch A) • red in color (lots of mitochondria, myoglobin & blood vessels) • split ATP at very fast rate; used for walking and sprinting • Fast glycolytic (fast-twitch B) • white in color (few mitochondria & BV, low myoglobin) • anaerobic movements for short duration; used for weight-lifting Principles of Human Anatomy and Physiology, 11e
Things that Interfere with the NMJ • Botulinum Toxin (Botox) blocks release of neurotransmitter at the NMJ so muscle contraction can not occur • bacteria found in improperly canned food • death occurs from paralysis of the diaphragm • Relaxes facial muscles to reduce appearance of wrinkles • Curare (plant poison used on poison arrows) • causes muscle paralysis • used to relax muscle during surgery
Anabolic Steroids • Similar to testosterone • Increases muscle size, strength, and endurance • Side Effects: • liver cancer • kidney damage • heart disease • mood swings • facial hair & voice deepening in females • atrophy of testicles & baldness in males Principles of Human Anatomy and Physiology, 11e
CARDIAC MUSCLE TISSUE - Overview • Cardiac muscle tissue is found only in the heart wall • Its fibers are arranged similarly to skeletal muscle fibers. • Cardiac muscle contractions last longer than the skeletal muscle twitch. • Cardiac muscle fibers contract when stimulated by their own autorhythmic fibers. • On average, contract 75 times per minute Principles of Human Anatomy and Physiology, 11e
SMOOTH MUSCLE • Smooth muscle tissue is nonstriated and involuntary. Principles of Human Anatomy and Physiology, 11e
Two Types of Smooth Muscle • Visceral (single-unit) • in the walls of small blood vessels • Multiunit • found in large arteries, large airways, and attached to hair follicles Principles of Human Anatomy and Physiology, 11e
Regeneration of Muscle • Skeletal muscle fibers cannot divide after 1st year • Cardiac muscle fibers cannot divide or regenerate • Smooth muscle fibers CAN regenerate • new fibers can form from stem cells in blood vessel walls Principles of Human Anatomy and Physiology, 11e
Aging and Muscle Tissue • Skeletal muscle starts to be replaced by fat beginning at 30 • “use it or lose it”: do free weight exercises • Results in slowing of reflexes & decrease in maximal strength Principles of Human Anatomy and Physiology, 11e
Diseases and Disorders: Myasthenia Gravis • Progressive autoimmune disorder that blocks receptors at the neuromuscular junction • More common in women 20 to 40 with possible line to thymus gland tumors • Begins with double vision & swallowing difficulties & progresses to paralysis of respiratory muscles Principles of Human Anatomy and Physiology, 11e
Muscular Dystrophies • Inherited, muscle-destroying diseases • Sarcolemma tears during muscle contraction • Mutated gene is on X chromosome so problem is with males almost exclusively • Appears by age 5 in males and by 12 may be unable to walk Principles of Human Anatomy and Physiology, 11e
Fibromyalgia • Fibromyalgia is a painful disorder that affects people aged 25-50, 15 times more common in women (genetic) • Without pressure, muscles are painful, tender, and stiff • Fatigue, poor sleep, headaches, depression results • Treatment includes exercise, stress reduction, heat, massage, pain meds
Abnormal Contractions • Spasm = involuntary contraction of single muscle • Cramp = a painful spasm • Tic = involuntary twitching of muscles normally under voluntary control--eyelid or facial muscles • Tremor = rhythmic, involuntary contraction of opposing muscle groups • Fasciculation = involuntary, brief twitch of a motor unit visible under the skin Principles of Human Anatomy and Physiology, 11e
Atrophy and Hypertrophy • Atrophy • wasting away of muscles • caused by disuse (disuse atrophy) or severing of the nerve supply (denervation atrophy) • Hypertrophy • increase in the diameter of muscle fibers • resulting from very forceful, repetitive muscular activity Principles of Human Anatomy and Physiology, 11e
Plantar Fascitis • Plantar fascitis, or painful heel syndrome, is swelling and inflammation due to chronic irritation of the heel bone (walking, jogging, wearing high heels) • Treated by ice, heat, stretching, weight loss, prosthetics, steroids, or surgery Principles of Human Anatomy and Physiology, 11e
Shin Splints • Shin splints refers to pain along the tibia, caused by stress fractures due to vigorous activity • Treated with ice, rest, and muscle strengthening activities
Pulled Hamstrings • A strain or tear of the hamstring muscles – a common sports injury • Accompanied by bruising, tearing, rupture of blood vessels, and pain Principles of Human Anatomy and Physiology, 11e