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Learn about the pathogenesis and control of feline infectious enteritis virus, canine parvovirus type 2, and porcine parvovirus. Explore the diseases caused in cats, dogs, and pigs, along with the antigenicity and host range of each virus.
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PARVOVIRIDAE PETER H. RUSSELL, BVSc, PhD, FRCPath, MRCVS Department of Pathology and Infectious Diseases, The Royal Veterinary College, Royal College Street, London NW1 OTU. E-mailWeb site
LEARNING OBJECTIVESStudents should be able to: • Relate the pathogenesis of feline infectious enteritis virus to its control • Explain the origins of canine parvovirus type 2 and its role in canine disease • Describe the importance and control of porcine parvovirus as a reproductive pathogen • List the species and disease conditions in which papilloma viruses are implicated
FELINE PARVOVIRUS DISEASE AND PATHOGENESIS:
FELINE PARVOVIRUS DIAGNOSIS:
FELINE PARVOVIRUS HOST RANGE : All felidae; mustelidae (mink) and some procyonidae (racoons and panda).
FELINE PARVOVIRUS ANTIGENICITY & CONTROL:
CANINE PARVOVIRUSTYPE 2 DISEASE AND PATHOGENESIS: Infection via oropharyngeal route followed by viraemia. Initially, there were two distinct syndromes associated with CPV-2: (1) targeted at rapidly dividing myocardial cells, (2) at the rapidly dividing cells in the crypt epithelium of the small intestine.
CANINE PARVOVIRUSTYPE 2 DIAGNOSIS:
CANINE PARVOVIRUSTYPE 2 HOST RANGE Dogs (but CPV-2a & 2b can cause disease in cats - see below)
CANINE PARVOVIRUSTYPE 2 ANTIGENICITY & CONTROL:
PORCINE PARVOVIRUS DISEASE AND PATHOGENESIS
PORCINE PARVOVIRUS HOST RANGE: pigs
PORCINE PARVOVIRUS EPIZOOTIOLOGY:
PORCINE PARVOVIRUS ANTIGENICITY & CONTROL:
SUMMARY • Cause serious diseases in cats (enteritis/ panleucopenia), dogs (myocarditis/ enteritis) and pigs (SMEDI). • Pathogenesis is related to the requirement for rapidly dividing cells for virus replication • Vaccines available for each disease which prevent viraemia & hence destruction of rapidly dividing cells.