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Protein synthesis simulation. Today, we will turn the classroom into a working cell analogy!. Essential Question. How do tRNA and ribosomes work together to create a protein from an mRNA strand?. Our goals. Activity goal:
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Protein synthesis simulation Today, we will turn the classroom into a working cell analogy!
Essential Question • How do tRNA and ribosomes work together to create a protein from an mRNA strand?
Our goals • Activity goal: • As a group, you will build a “protein.” (It will be something you can take home!) • Learning goal: • To solidify our understanding of protein synthesis through the simulation activity.
Norms • No one of us is as smart as all of us together. • Help other group members without doing their work for them. • Every member of the group must carry out their own role.
Multiple abilities needed for your group to be successful • Ask questions that clarify or push the science conversation deeper. • Apply your thinking to what really happens in a cell. • Follow detailed instructions. • Ask group members to follow the safety rules and procedures. • Develop a work plan and follow it. • Organize the information you collect. • Reflect on the work done during the activity.
Productive Team Work What I’m listening and looking for: • Each group member is following their own role. • Each group member is contributing to completing the task. • Each group member is following safety rules. (GOGGLES OVER YOUR EYES!)
Step 1 : Familiarize yourself with your role • Read your own role. Make sure you understand what you are doing. • (Wear your “nametags” after you read them!) • Complete your half-sheets. • Build your protein. • Clean up. • Answer analysis questions in COMPLETE SENTENCES in your lab notebook.
Step 2 : Familiarize your group with your role • Read out your role to your group members. Make sure they know what you are doing. • Wear your “nametag” after you’re done reading.
Stick to your role! • tRNAs, mRNAs, and ribosomal subunits all do different jobs. They can’t transform into each other. • Only ONE group member (tRNA) should be out of their seat retrieving materials. • mRNA should write down the translated instructions.
Procedures • Follow the instructions on the golden rod sheet. • Complete your half-sheets. • Build your protein. • Clean up. • Answer analysis questions in COMPLETE SENTENCES in your lab notebook.
Lab Tips • EVERYONE in the group should help decode the DNA and mRNA strands. • READ LABELS CAREFULLY! Some “amino acids” will be your measuring equipment, others will be substances to add into your measuring equipment.
Clean Up! • Rinse out all used materials. • Return materials to counter (threonineand phenylalanine). • Ask me for plastic bags if you want to take your protein home. • mRNA: Return role cards and Protein Synthesis Table to Ms. Lee.