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LDL-c levels in homozygous autosomal dominant hypercholesterolaemia patients. 25. 2 null alleles. 20. 1 null allele, 1 defective allele. 2 defective alleles. 15. 10. LDL-c levels (mmol/L). 5. 0. Before lipid-lowering therapy. After lipid-lowering therapy.
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LDL-c levels in homozygous autosomal dominant hypercholesterolaemia patients 25 2 null alleles 20 1 null allele, 1 defective allele 2 defective alleles 15 10 LDL-c levels (mmol/L) 5 0 Before lipid-lowering therapy After lipid-lowering therapy Sjouke et al., Eur Heart J 2014