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Familial Hypercholesterolaemia

Familial Hypercholesterolaemia. Dr Rosemary Croft 15 th May 2013. Familial Hypercholesterolaemia. 1 in 500 affected Genetic – autosomal dominant Untreated 50 develop CVD by age 55 DNA test costs £320 Treat with high intensity statin £2,700 per QALY

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Familial Hypercholesterolaemia

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  1. Familial Hypercholesterolaemia Dr Rosemary Croft 15thMay 2013

  2. Familial Hypercholesterolaemia • 1 in 500 affected • Genetic – autosomal dominant • Untreated 50 develop CVD by age 55 • DNA test costs £320 • Treat with high intensity statin • £2,700 per QALY • FH co-ordinator arranges family screening & adds to national database

  3. Consider Diagnosis if Family history or High Cholesterol • Do full fasting lipid screen • If LDL>5.5 and trigs <2.0mmol/l • Refer to virtual lipid clinic using proforma on choose & book

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