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CELLULAR RESPIRATION. Glycolysis http://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_glycolysis_works.html. Walsh Ingraham battle iron man http://www.youtube.com/watch?v=MTn1v5TGK_w. ï‚®. C 6 H 12 O 6. +. 6O 2. 6CO 2. +. 6H 2 O. +. ATP.
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CELLULAR RESPIRATION Glycolysis http://highered.mcgraw-hill.com/sites/0072507470/student_view0/chapter25/animation__how_glycolysis_works.html Walsh Ingraham battle iron man http://www.youtube.com/watch?v=MTn1v5TGK_w
C6H12O6 + 6O2 6CO2 + 6H2O + ATP CELLULAR RESPIRATION AS A REDOX REACTION loses e- gains e- oxidized reduced + – + + H oxidation reduction H
Cellular Respiration ANAEROBIC A. Glycolysis: AEROBIC B. Pyruvate Oxidation & Citric Acid Cycle (Kreb Cycle) C. Oxidative Phosphorylation
Cellular RespirationStage 1:Glycolysis 2007-2008
CH2OH O Glucose 1 ATP hexokinase ADP CH2 O P O Glucose 6-phosphate 2 phosphoglucose isomerase CH2 P O CH2OH O Fructose 6-phosphate 3 ATP phosphofructokinase P O CH2 CH2 O P O ADP Fructose 1,6-bisphosphate aldolase 4,5 H O CH2 P isomerase C O C O Dihydroxyacetone phosphate Glyceraldehyde 3 -phosphate (G3P) CHOH CH2OH CH2 O P NAD+ Pi NAD+ Pi 6 glyceraldehyde 3-phosphate dehydrogenase NADH NADH P O O CHOH 1,3-Bisphosphoglycerate (BPG) 1,3-Bisphosphoglycerate (BPG) CH2 O P 1st Glucose Priming
P O CH2 CH2 O P O ADP 4,5 Fructose 1,6-bisphosphate aldolase H O CH2 P isomerase C O C O Dihydroxyacetone phosphate Glyceraldehyde 3 -phosphate (G3P) CHOH CH2OH CH2 O P NAD+ Pi NAD+ Pi 6 2nd Cleavage
Energy Harvest (5 reactions) G3P C-C-C-P Pi Pi NAD+ NAD+ 6 NADH NADH 7 ADP ADP O- phosphoglycerate kinase C ATP ATP CHOH 3-Phosphoglycerate (3PG) 3-Phosphoglycerate (3PG) CH2 P O 8 O- phosphoglycero-mutase O C H C O P 2-Phosphoglycerate (2PG) 2-Phosphoglycerate (2PG) CH2OH O- 9 H2O H2O enolase C O O C P Phosphoenolpyruvate (PEP) Phosphoenolpyruvate (PEP) CH2 O- 10 ADP ADP C O pyruvate kinase Payola!Finally some ATP! ATP ATP C O CH3 Pyruvate Pyruvate
Glycolysis summary ENERGY INVESTMENT -2 ATP G3P C-C-C-P ENERGY PAYOFF 4 ATP like $$in the bank NET YIELD
Glycolysis Breaking down glucose glucose pyruvate 6C 3C 2x In thecytosol?Why doesthat makeevolutionarysense? That’s not enoughATP for me!
Evolutionary perspective Prokaryotes Anaerobic atmosphere Prokaryotes that evolved glycolysis are ancestors of all modern life ALL cells still utilize glycolysis You meanwe’re related?Do I have to invitethem over for the holidays?