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Hans Torp NTNU, Norway. TTK 4165. Signalbehandlingsteknikker i medisinsk bildediagnostikk Signal Processing in Medical Imaging Faglærer: Hans Torp Institutt for sirkulasjon og bildediagnostikk. Hans Torp NTNU, Norway. lecture overview. Physical principles of ultrasound
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Hans Torp NTNU, Norway TTK 4165 Signalbehandlingsteknikker i medisinsk bildediagnostikk Signal Processing in Medical Imaging Faglærer: Hans Torp Institutt for sirkulasjon og bildediagnostikk
Hans Torp NTNU, Norway lecture overview • Physical principles of ultrasound • Ultrasound imaging • Ultrasound Doppler and flow imaging • Overview TTK4165
Echoes from tissue structures are received and displayed First Cardiac trials by Edler and Hertz in 1953 Hans Torp NTNU, Norway Ultrasonic M-Mode (Motion Mode)
Hans Torp NTNU, Norway Real-time Ultrasound B-mode 1974 Vis film N. Bom & al. “Multiscan EchoCardiograph” Ultrasound in Medicine aug. 74
Blood velocity Mitral inflow Normal relaxation Delayed relaxation Doppler blood flow meter Pedof 1976
Fourier transform - measure bloodflow • Gaussian Random process - ultrasound signal • Analog computer diff. equation solver- model of the cardiovascular system • Bernouli equation- from blood velocity to pressure
Ultrasound probe Focusing Steering and Focusing 50-200 elements
2 Received Echoes from close objects 1 Objects probe elements
A / D 134 134 134 134 134 134 134 134 134 134 134 134 134 134 134 A / D 134 134 134 134 134 134 134 134 134 134 134 134 134 134 134 A / D 134 134 134 134 134 134 134 134 134 134 134 134 134 134 134 A / D 134 134 134 134 134 134 134 134 134 134 134 134 134 134 134 A / D 134 134 134 134 134 134 134 134 134 134 134 134 134 134 134 A / D 134 134 134 134 134 134 134 134 134 134 134 134 134 134 134 A / D 134 134 134 134 134 134 134 134 134 134 134 134 134 134 134 Digital Beam Former #Channels: 128 # samples per channel: 10.000 • Data per scanline: 2*10.000*128 = 2.5 Mb • Data per image: 2.5*100 = 250 Mb • Data per second: 40* 250 Mb = 10 Gb
1996 System Five 128 channels Elektronic scanning Mekanisk scanning 2000 Vivid 7 128 kanaler Elektronisk scanning 1986 CFM 700 5 channels Mekanisk scanning
Hans Torp NTNU, Norway Real-time 2D B-modeWall motion assessment ))) )))
Linear array High resolution Limited width Curve-linear array Large image width Large near field Phased array Small footprint 90 deg. sector format Hans Torp NTNU, Norway Ultrasound Probes
Heart, 4 chamber view Kidney Fetus 3 ½ mnd Liver Twin fetus Ultrasound imaging can be applied to almost all human organs Ultrasound imaging: Measure dimensions, areas, volumes Study anatomical details Assessment of muscle contraction Heart-valve function
Probe-diameter D F: Focal depth L Image resolution D aperture F-number f# = F/D Wavelength: L ”Dot-size”: f# L F: Focal depth Camera example L = 0.9 e-3 mm f# = 5.6 Resolution: 0.005 mm ~ 50000 dpi Infrared camera gives lower resolution Ultrasound example L = 0.5 mm (3 MHz) f# = 8cm/2cm= 4 Resolution: 2 mm ~ 125 dpi Larger probe -> improved resolution Higher frequency -> improved resolution
Embryo 7 weeks. Ca 13 mm length • Computer-simulated ultrasound image • Higher frequency -> better resolution
3D Transvaginal ultrasoundThe Lancet:In-vivo three-dimensional ultrasound reconstructions in the embryonic and early fetal periodHarm-Gerd Blaas 1, Sturla H. Eik-Nes 1, Sevald Berg 2, Hans Torp 2;
18 weeks Limb development in Norway 20th century 12 weeks
PW Doppler: Velocity from one point Color flow imaging: Velocities in the whole image Color M-mode: Velocities along a line Color Doppler velocity imaging
Curved M-mode Systole Atrial systole Early relax. Hans Torp NTNU, Norway Tissue Velocity Imaging Moving upward Moving downward
Wall motion quantification Curved M-mode Systole Atrial systole Early relax. Strain rate Tissue velocity Strain rate v1 SR L v2 Shortening No change Elongation Adapted from J-U. Voigt and A. Heimdal
Real-time 3D imaging2D matrix array 50 x 1 elements • 32-192 elements in a 1D array • 32*32 ... 96*96 elements in a 2D array • 1000 - 10000 elements • Cable • Electronics • Beamformer 50 x 50 =2500 elements
Azimuth Elevation Sanntid 3D
4D Volume Imaging Increased elevation width Standard setup • No ECG gating • Volume rendering / orthogonal slicing • Volume size: ~20 x 80º / ~35 x 45º • Volume rate: 17-25
4D Color Imaging (ECG Gated) • Gated from 7 heart beats • High frame rates (17-35 frames / second) • High Color sensitivity • High Color resolution
TTK4165 Overview • Pulse Echo principle • Ultrasound beamforming • General imaging system • Ultrasound imaging system • Doppler – blood velocity measurement and imaging • Patient safety issues • Ultrasound contrast imaging • 3D imaging