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How does sleep affect the immune system?

How does sleep affect the immune system?. By: Katherine Ingram. http://www.miravalresorts.com/blog/post.cfm/sleep-better-this-year. http://uhaweb.hartford.edu/bugl/immune.htm. Normal Sleep Patterns. Amount based on Age Genetics Sleep need vs. sleep debt Quality.

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How does sleep affect the immune system?

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  1. How does sleep affect the immune system? By: Katherine Ingram http://www.miravalresorts.com/blog/post.cfm/sleep-better-this-year http://uhaweb.hartford.edu/bugl/immune.htm

  2. Normal Sleep Patterns Amount based on Age Genetics Sleep need vs. sleep debt Quality http://www.sleepfoundation.org/article/how-sleep-works/how-much-sleep-do-we-really-need https://encrypted-tbn2.gstatic.com/images?q=tbn:ANd9GcTrntXKJU6rKcnJyK-r5v-8-W00omX07DL30W2zdI1es0hbKa7IoQ

  3. Normal Immune Responses • Inflammation- response to pathogens or an injury (2nd line defense) • Attempt at self- protection • Part of innate immunity • Acute vs. chronic • Macro • Specialized Cells • Lymphocytes, macrophages A- http://en.wikipedia.org/wiki/Inflammation B- http://www.pathologystudent.com/?p=2186 C- http://en.wikipedia.org/wiki/Macrophage

  4. Recent Studies- Short Term Effects on Macro Level A- TLR receptor http://www.nature.com/nrn/journal/v3/n3/fig_tab/nrn752_F1.html B- White blood cell http://en.wikipedia.org/wiki/White_blood_cell

  5. Long Term Effects on Immune System • Inflammation leads to serious diseases… • Cardiovascular disease • Diabetes • Stroke • Hyperactivity of the Immune System • Less efficient A B A- http://www.dedeep.com/circulatory-system-heart-diagram/ B- http://www.rightinginjustice.com/news/2011/12/07/metformin-may-help-protect-against-diabetes-associated-cancers/

  6. "How Much Sleep Do We Really Need?" National Sleep Foundation. N.p., n.d. Web. 26 Jan. 2014. <http://www.sleepfoundation.org/article/how-sleep-works/how-much-sleep-do-we-really- need>. Mercola, Joseph, Dr. "New Insights into Links Between Immune Function and Sleep." Mercola. Ed. Joseph Mercola, Dr. N.p., n.d. Web. 26 Jan. 2014. <http://articles.mercola.com/sites/articles/archive/2012/08/04/immune-system-and-sleep- deprivation.aspx>. Modolfsky, H., et al. Effects of sleep deprivation on human immune functions. Toronto: University of Toronto, 1989. Print. Perelman School of Medicine at the University of Pennsylvania. "Sleep- deprived mice show connection with diabetes, age." Science Daily. N.p., 11 Dec. 2013. Web. 26 Jan. 2014. <http://www.sciencedaily.com/releases/2013/12/131211185215.htm>. "Poor Sleep Tied to Inflammation, A Risk Factor for Heart Disease, Stroke." Medical News Today. MediLexiconInternational, 15 Nov. 2010. Web. 26 Jan. 2014. <http://www.medicalnewstoday.com/articles/207877.php>. Smith, Melinda, Lawrence Robinson, and Robert Segal. "How Much Sleep Do You Need? Sleep Cycles & Stages, Lack of Sleep, and How to Get the Hours You Need." Help Guide. N.p., Oct. 2013. Web. 27 Jan. 2014. <http://www.helpguide.org/life/sleeping.htm>. University of Helisinki. "New links between sleep deprivation, immune system discovered." Science Daily. ScienceDaily, 23 Oct. 2013. Web. 22 Jan. 2014. <http://www.sciencedaily.com/releases/2013/10/131023183908.htm>. "What is Inflammation? What causes Inflammation?" Medical News Today. MediLexicon International, 31 July 2012. Web. 22 Jan. 2014. <http://www.medicalnewstoday.com/articles/248423.php>. Citations

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