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PARP-1+/+ p53-/-

Tumor formation in nude mice injected by oncogenic ras -transduced primary (PARP-1-/-; p53-/-) MEFs is considerably delayed. + Matrigel. 6. 0. 0. PARP-1-/- p53-/-. 5. 0. 0. PARP-1+/+ p53-/-. PARP-1+/+ p53-/-. 4. 0. 0. Tumour volume (mm 3 ). 3. 0. 0. PARP-1-/- p53-/-. 2.

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PARP-1+/+ p53-/-

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  1. Tumor formation in nude mice injected by oncogenic ras-transduced primary(PARP-1-/-; p53-/-)MEFs is considerably delayed + Matrigel 6 0 0 PARP-1-/- p53-/- 5 0 0 PARP-1+/+ p53-/- PARP-1+/+ p53-/- 4 0 0 Tumour volume (mm3) 3 0 0 PARP-1-/- p53-/- 2 0 0 1 0 0 0 0 5 1 0 1 5 2 0 2 5 Time (days) Conde, C. et al. (2001) EMBO J. 20, 3535-43

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