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Acquiring Immunity. Long Term Protection. Individual Activity (means no talking). Read Acquiring Specific Immunity at top of p317 of Biology 2. Questions. Why is Specific Immunity also called Acquired Immunity??
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Acquiring Immunity Long Term Protection
Individual Activity (means no talking) • Read Acquiring Specific Immunity at top of p317 of Biology 2.
Questions • Why is Specific Immunity also called Acquired Immunity?? • Specific immunity is Acquired Immunity (you only develop immunity following exposure. • What is the difference between active and passive immunity? • Active – antibodies are made in the body • Passive – antibodies are produced in one person and transferred to another
Individual Activity (still means no talking) • Read section Active Immunity on p317-318
Questions • What is natural active immunity? • Antibodies are produced in the body (naturally) following exposure to a pathogen. • What is induced active immunity? • Antibodies made after immunisation with toxoid or with killed or treated organisms (vaccines). • REVISE IMMUNE RESPONSE - Label diagram and paste into your notes.
Cell Mediated Response Antibody Mediated Response
Individual Activity (still means no talking) • Read section Eradicating a Disease by Vaccination on p318-320
Questions • Vaccination is the process of introducing the vaccine into the body where as Immunisation is the immune response to the vaccine that results in immunity. What is a vaccine? • Vaccines (dead or live but weakened(attenuated) pathogens and synthetic antigens) are used to activate the immune system against that specific disease, without causing the disease. Vaccines have the same antigens as the infective pathogen. Vaccines are usually injected or ingested. • Copy this graph into your notes. With reference to the Immune System and this graph, what is Immunisation?
Usually involves a series of injections to bring on lasting immunity. This is the immunisation program and involves: • A first vaccination, in which the vaccine in introduced into the body for the first time • A primary response, during which plasma cells slowly produce small amounts of antibodies, resulting in short term immunity. Some memory cells are produced. This takes about 10 days and the amount of antibodies quickly declines once infection has cleared • A second vaccination, in which a second vaccine (or booster) is introduced into the body. Existing memory cells respond. • A secondary response, during which plasma cells rapidly produce large amounts of antibodies much more quickly (approximately 3 days) and in much greater amounts. The level of antibodies in the secondary response remain much higher for longer than the primary response resulting in long term immunity.
Questions • What is a Toxoid? • Some pathogens secrete toxins which can be treated with Toxoidsin a similar way to vaccines. • Give some examples of Vaccine preventable diseases. • Tetanus, Diphtheria, Pertussis (Whooping Cough), Hepatitis A, Hepatitis B, Varicella Zoster (Chicken Pox), Poliomyelitis, Measles, Mumps, Rubella (German Measles), Influenza, there are many more
Individual Activity (still means no talking) • Read section Passive Immunity and Rabbits as antibody making machines on p320-321
Questions • What is natural passive immunity? • Antibodies acquired by baby across placenta or in mother’s milk • What is induced passive immunity? • Antibodies acquired through injection of Immunoglobulins (antibodies) • Copy and Label the following diagram
Memory B and T cells No Memory Cells
Individual Activity (still means no talking) • Read section Adverse Event Associated with Immunity on p322-323
IMMUNE DOCUMENTRY http://www.youtube.com/watch?v=0u6z6yFxahg&feature=related http://www.youtube.com/watch?v=OBMIkfMMTHs&feature=relmfu http://www.youtube.com/watch?v=gGemkOYPtmw&feature=relmfu - skip http://www.youtube.com/watch?v=ysw_Zs-ydP8&feature=relmfu http://www.youtube.com/watch?v=lZWOh3NEsag&feature=relmfu http://www.youtube.com/watch?v=_49z0Xf235Q&feature=fvwrel http://www.youtube.com/watch?v=ouqVl6CpW-U&feature=relmfu http://www.youtube.com/watch?v=ouqVl6CpW-U&feature=fvwrel http://www.youtube.com/watch?v=qIH9T-GBjm4&feature=relmfu http://www.youtube.com/watch?v=SAsTwG5Mxow&feature=relmfu