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Global Epidemiologic Variability of EGFR Mutation NSCLC

Global Epidemiologic Variability of EGFR Mutation NSCLC. Keunchil Park, MD, PhD Professor Division of Hematology/Oncology Department of Medicine Sungkyunkwan University School of Medicine Samsung Medical Center Seoul, Korea.

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Global Epidemiologic Variability of EGFR Mutation NSCLC

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  1. Global Epidemiologic Variability of EGFR Mutation NSCLC Keunchil Park, MD, PhD Professor Division of Hematology/Oncology Department of Medicine Sungkyunkwan University School of Medicine Samsung Medical Center Seoul, Korea Epidemiologic studies can be subject to selection bias. Real-life data may differ.

  2. EGFR Epidemiologic Studies in Asia *Less than 20 pack-years or never smokers ARMS = amplification-refractory mutation system; EGFR = epidermal growth factor receptor; PNA-LNA = peptide nucleic acid-locked nucleic acid a. Yang PC, et al. ASCO 2012. Abstract 1534. b. Liam CK, et al. J Thorac Oncol. 2013;8(6):766-772. c.Choi YL, et al. PLoS One. 2013;8(2):e56011. d. Tanaka T, et al. Int J Cancer. 2010;126(3):651-655.

  3. EGFR Mutation Rates in Asia PIONEER (single study)[a] a. Yang PC, et al. ASCO 2012. Abstract 1534. b. Liam CK, et al. J Thorac Oncol. 2013;8(6):766-772. c.Choi YL, et al. PLoS One. 2013;8(2):e56011. d. Tanaka T, et al. Int J Cancer. 2010;126(3):651-655.

  4. EGFR Epidemiologic Studies in Asia *Less than 20 pack-years or never smokers a. Yang PC, et al. ASCO 2012. Abstract 1534. b. Liam CK, et al. J Thorac Oncol. 2013;8(6):766-772. c.Choi YL, et al. PLoS One. 2013;8(2):e56011. d. Tanaka T, et al. Int J Cancer. 2010;126(3):651-655.

  5. Predictors of EGFR Mutation a. Yang PC, et al. ASCO 2012. Abstract 1534. b. Liam CK, et al. J Thorac Oncol. 2013;8(6):766-772. c.Choi YL, et al. PLoS One. 2013;8(2):e56011. d. Tanaka T, et al. Int J Cancer. 2010;126(3):651-655.

  6. EGFR Mutation Rates in the West a. Rosell R, et al. N Engl J Med. 2009;361(10):958-967; b.de Mello RA, et al. Tumour Biol. 2012;33(6):2061-2068; c. Smits AJ, et al. Cell Oncol (Dordr). 2012;35(3):189-196; d. Boch C, et al. BMJ Open. 2013;3(4):e002560; e.Cote ML, et al. Thorac Oncol. 2011;6(3):627-630.

  7. Temporal Trends in EGFR Mutation Test in Korea P = .001 P < .001 Choi YL, et al. PLoS One. 2013;8(2):e56011.

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