5.03k likes | 5.05k Views
This comprehensive guide delves into occupational exposure risks, presenting key buzzwords and information crucial for board review preparation. From chemical-induced diseases to toxic substances, it covers a wide array of occupational health challenges.
E N D
Med Tox Board Review:Buzzwords for the Boards GP Daubert 2014
“Egg-shell” calcifications of hilar lymph nodes, increase risk of tuberculosis, upper lung disease
Pneumoconiosis with hilar adenopathy; clinically and pathologically identical to sarcoidosis except no eye involvement; lymphocyte transformation test
Porphyria, pemba yara, spongiform encephalopathy, outbrake in Turkey in 1956
Isolated thrombocytopenia, “bathtub refinisher’s lung”, sensitizing agent - largest recognized cause of occupational asthma
Pesticide operator with sterility, altered sex ratio in offspring
Dibromochloropropane • (DBCP) • Re: “Da Balls Can’t Produce”
Hypertension, Saturnine gout, renal failure, microcytic anemia
“Silver solderers”, proximal RTA, itai-itai disease in Jintsu River basin, acute lung injury, renal failure
Perforated nasal septum, lung cancer, painless ulcers, “blackjack disease”, Type IV hypersensitivity dermatitis
Hairdresser with hearing loss, renal failure, methemoglobinemia
The cholera toxin activates cAMP, which intern stimulate CFTR causing a dramatic efflux of ions and water from infected enterocytes. • What popular ‘pop’ band was associated with this disease?
Solvent, epoxide metabolite (hepatotoxicity), “Degreaser’s flush”, trigeminal neuralgia
Viscous rayon, increase rate of atherosclerosis; disulfiram and metam sodium metabolites; basal ganglia toxin; associated with spontaneous abortions; decreased spermatogenesis, craniofacial abnormalities; optic nerve and retinal degeneration
The percentage of sick people who are identified as having the condition • or • The likelihood of a test being positive if the condition is present
A result of 100% means that the test recognizes all healthy people as healthy • or • The likelihood of the unaffected individuals correctly having a negative test
Condition + - True Positive False Positive(Type I error) + → PPV Testoutcome False Negative(Type II error) True Negative - → NPV ↓Sensitivity ↓Specificity
Condition Yes No → Absolute Risk Exposed (ARE) A/(A+B) B A Yes Risk Factor → Absolute Risk Unexposed (ARU) C/(C+D) C D No Attributable Risk (Risk Difference) = ARE – ARU Relative Risk = ARE/ARU Odds Ratio = (A/C)/(B/D)
Solvent, acute CNS depression, arrhythmias, AML, Hodgkin’s lymphoma, paroxysmal nocturnal hemoglobinuria
Wastewater treatment worker with sensory and motor distal axonal neuropathy (axonopathy)
What singer is associated with Hymonoptera-induced anaphylaxis?
Wastewater treatment worker with sensory and motor distal axonal neuropathy (axonopathy), also has blue discoloration of hands and feet, desquamation, and pulmonary irritation
Ginger Jake, NTE inhibitor, sensory-motor neuropathy, 1960 Morocco disaster