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Biomolecular and Cellular Engineering

Biomolecular and Cellular Engineering. Microbes Enzymes Biomolecules. Metabolic Engineering . Synthetic Biology . Protein Engineering . Directed Evolution . Biopolymer Antibody.

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Biomolecular and Cellular Engineering

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  1. Biomolecular and Cellular Engineering Microbes Enzymes Biomolecules Metabolic Engineering Synthetic Biology Protein Engineering Directed Evolution Biopolymer Antibody Nano-Devices, Sensors, Environmental, Biosynthetic and Biomedical Applications

  2. Biomolecular Tools Research Interest

  3. Artificial Cellulosomes Bayer et al., 2006 • Found in anaerobic microbes • Hydrolyze cellulose up to 50-fold faster due to synergy • 3. Interaction between dockerinto cohesin is species specific

  4. Synthetic Yeast Consortia

  5. Virus detection and drug discovery Influenza

  6. Translation Uncoating RNA replication Nucleus In situ Monitoring of Virus Replication Using Molecular Beacons Fixation with para-formaldehyde and permeabilization Triton X-100

  7. In vivo detection of Coxsackie B6 virus in BGMK cells Cells infected with 103 PFU, M.O.I.≈ 0.5 (15 min to 18 hr) PlasDIC (t = 0 min) Yeh et al. PNAS, 17522-17525, 2008

  8. Acknowledgement 9 Graduate Students and 1 Postdoc

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