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Lecture on Skeletal Muscle Tissue

Lecture on Skeletal Muscle Tissue. www.AssignmentPoint.com. Main objectives:. Describe the distinguishing characteristics of the different muscle tissues Discuss the organization of skeletal muscle Explain the micro-anatomy of a skeletal muscle fiber

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Lecture on Skeletal Muscle Tissue

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  1. Lecture onSkeletal Muscle Tissue www.AssignmentPoint.com

  2. Main objectives: • Describe the distinguishing characteristics of the different muscle tissues • Discuss the organization of skeletal muscle • Explain the micro-anatomy of a skeletal muscle fiber • Describe the fascicle arrangement in different types of muscle • Review general muscle terminology

  3. One of the 4 primary tissue types How many subtypes? Made up of _____ tissue types. > 700 skeletal muscles Word roots: sarco mys Muscle tissue vs. Muscle as an organ

  4. Function of Skeletal Muscles • Skeletal movement • Posture and body position • Support of soft tissues • Guarding of entrances & exits • Maintenance of body temperature

  5. Gross Anatomy Each skeletal muscle is wrapped by 3 concentric layers of connective tissue.

  6. Epi-, Peri-, and Endomysium Are interwoven - Go over into tendon Distinguish between: Tendon Aponeurosis Ligament Function: Protection Blood supply Innervation Fig 9-1

  7. Nerveand Blood Vessel Supply Skeletal muscles are rich in nerves and blood vessels Chemical communication at Synapsis (neuromuscular junction) Synaptic terminal of axon meets motor end plate of muscle cell Coiled capillaries are able to adapt to changes in length of muscle fiber Fig 9-2

  8. Microanatomy of Skeletal Muscle Fibers Some vocabulary: Skeletal muscle fiber or myofiber Sarcolemma Sarcoplasm Sarcoplasmic reticulum Myofibril Myofilaments Fig 9-3

  9. Myofilaments Myofiber ( 100µm) Myofibrils ( 1-2 µm) Myofilaments Actin & Myosin

  10. Sarcomeres Thick and Thin Filaments are organized in repeating functional units = ______ Each myofibril has linear arrangement of ~ 10,000 sarcomers Banded appearance (striation) due to arrangement of thick and thin filaments Interaction of thick and thin filaments responsible for skeletal muscle fiber contraction

  11. Sarcomere Structure Z - line I - band = LIght band A- band = dArk band

  12. Thin Filament: Actin F-actin G-actin

  13. Thick Filament: Myosin

  14. Development of Myofibers from Myoblasts Some Myoblasts do not fuse satelite cells in endomysium regeneration of muscle

  15. Motor Units = All muscle fibers that are controlled by a single motor neuron The lower the ratio of muscle fibers to neurons, the more precise the movement can be! Few cases 1: 1 relationship. Where? Most cases: many muscle fibers (up to 2,000) : 1 motor neuron. Where? Fig 9-12

  16. Muscle Control Muscle tone = Resting tension of skeletal muscles (continuous contraction of some motor units to maintain some muscle tension) Recruitment or Multiple motor unit summation Maximal tension production: ?

  17. Muscle Hypertrophy vs. Atrophy Hypertrophydue to anaerobic exercise Leads to increased muscle size - how? Atrophyif supply of myofilaments exceeds demand. Muscle fibers become smaller and weaker. Eventual death of muscle fibers is irreversible! Importance of Physical Therapy

  18. Three Types of Muscle Fibers 1) Fast (or White) Fibers Fast contraction after nervous stimulation Large diameter large glycogen reserve few mitochondria densely packed myofibrils Fatigue fast due to mainly anaerobic respiration

  19. 2) Slow (or Red) Fibers Slower but continuous contraction for extended periods Smaller diameter (~ half) contain myoglobin more capillaries more mitochondria Do not fatigue as fast due to ? Fig 9-13

  20. 3) Intermediate Fibers Have attributes inbetween fast and slow types Most skeletal muscles contain mixture of fiber types. Proportion of fast to slow depends on ___________? One motor unit only contains one fiber type Eye, hand: ____ fibers dominate Back, calf: ____ fibers dominate

  21. Organization of Skeletal Muscle Fibers Effect of individual muscle contractiondetermined by: • arrangement of muscle fibers • way of attachment to skeletal system Bundles of muscle fibers = Muscle fibers within 1 fascicle are parallel 4 types of fascicle organization

  22. Parallel Muscels Majority Spindle shaped with cord-like tendons Some flat bands with broad _____ on each end Examples: ?

  23. Convergent muscels Broad origin, pointed insertion Direction of pull can be varied: versatility!! Example

  24. Pennate Muscles: Unipennate One or more tendons run though muscle body Fascicles in oblique angle to tendon Can generate more tension Example

  25. Pennate Muscles: Bipennate & Multipennate Example Example

  26. Circular Muscles = Sphincters Concentric fibers adjust opening Examples: orbicularis occuli and oris

  27. Muscle Terminology Origin stationary Insertion moves Possible: multiple origins

  28. Types of Actions • flexion, extension • adduction, abduction • elevation, depression • rotation, circumduction • pronation, supination etc. . . . .

  29. Grouping of Muscles according to Primary Action Agonist = Prime Mover Antagonist (action opposes agonist) Synergists = Assistants of prime mover

  30. Naming of skeletal Muscles Orientation of fibers Size & shape Location Action Origin & / or insertion Specific features Use muscle name to help identify its location, appearance and function!

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