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National Institute of Biomedical Imaging and Bioengineering

National Institute of Biomedical Imaging and Bioengineering. Richard E. Swaja, Ph.D. National Institute of Biomedical Imaging and Bioengineering BERAC – April 26, 2002. National Institutes of Health. NCI NEI NHLBI NHGRI

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National Institute of Biomedical Imaging and Bioengineering

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  1. National Institute of Biomedical Imaging and Bioengineering Richard E. Swaja, Ph.D. National Institute of Biomedical Imaging and Bioengineering BERAC – April 26, 2002

  2. National Institutes of Health NCI NEI NHLBI NHGRI NIA NIAAA NIAID NIAMS NIBIB NICHD NIDCD NIDCR NIDDK NIDA NIEHS NIGMS NIMH NINDS NINR NLM FIC NCCAM NCMHD NCRR

  3. NIBIB History • Mandated on December 29, 2000 • Establishment Package – April 25, 2001 • First budget approved – January 10, 2002 • FY2002 Budget - $ 112 M ($45 + 67) • First RFA’s – February (First grant – April) • Currently – About 22 employees (30 in FY) • Web site – http://www.nibib.nih.gov • Director and Advisory Committee ?

  4. What’s Different? • Focus on enabling technologies with broad applications for disease and biological processes • Multi-disciplinary and collaborative research • Technology- and design-driven applications in addition to hypothesis-driven • Inter-agency and Intra-NIH coordination

  5. Sensors • Detector – transducer – actuator system • Biological, chemical, and mechanical detectors • Signal transduction and processing • Actuators for therapy and intervention • Integrated systems • Power sources • Biointerfaces • Model algorithms

  6. Nanotechnology and Microtechnology • BioMEMS and BioNEMS • Nanoparticles and nanomanufacturing • Detectors and sensors • Cell encapsulation • Molecular machines • Contrast agents • Probes • Targeted drug delivery • Gene transfer

  7. Biomaterials • Cell-level – Tissue engineering • Organogenesis • Bioreactors • Scaffolds • Stem cells • Macro-level • Devices • Prosthetics • Implants

  8. Computer Applications • Modeling and simulation • Robotics • Computer-assisted surgery • Signal analysis and processing • Telemedicine

  9. Imaging • Diagnostic and research (molecular/cellular) • Contrast agents • Multiple modalities • Signal analysis and processing • Data analysis and transmission • Image-guided intervention • Platform development • Devices and optimization • Biophotonics

  10. When to apply to the NIBIB • Research and development of enabling technologies and devices • Must have broad or multiple application to diseases or biological processes • For specific disease or clinical applications, apply to appropriate institute • Research must have biomedical application

  11. Current NIBIB BMI and BME Research Opportunities • Bioengineering Research Grants (BRG’s) • Bioengineering Research Partnerships (BRP’s) • RFA EB-02-001 (Molecular BMI) • RFA EB-02-002 (Sensor BME) • Participation in other RFA’s and PA’s

  12. Participation in RFA’s and PA’s • Basic technology development for diagnostic and molecular-level imaging (NCI) • Functional neural imaging (NIMH) • Non-invasive sensors (NIDDK) • Biomaterials development (NHLBI) • Bioterrorism (NIAID)

  13. Bioengineering Research Grants – PA-02-011 • R01 mechanism – Coordinated by BECON • Multi-disciplinary research applicable to biomedical problem • Single or small groups of investigators • Applications due on regular R01 dates – February 1, June 1, and October 1 • 102 BRG awards – Average = $330 k/yr

  14. Bioengineering Research Partnerships – PAR-02-010 • R01 mechanism – BECON coordinated • Requires multi-organizational, multi-disciplinary teams to conduct research • Next deadline – August 12 • 60 BRP awards - $ 880 k/yr • Partner with NIH grantee

  15. Phased Innovation Award – R21/R33 • Aimed at high-risk, innovative research • R21 – “Seed” money to “proof-of-principle” – 2 years - $100-150 k/yr. • R33 – Like R01 – 3 years – No limit but must justify budget • Check institute requirements – Some require package, some can apply separately

  16. NIBIB and DOE • Focus of NIBIB is on technology development • NIBIB focus areas are DOE strengths • BRG and BRP offer partnering opportunities for technologists (intramural) • R21/R33 provide opportunities for innovative research • Caveats and Opportunities

  17. www.nibib.nih.gov • What’s New • Contact information • Research opportunities • Training opportunities • Symposia and workshops • Calendar • Vacancy announcements • General information

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