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LC-MS of drugs of abuse and related compounds

LC-MS of drugs of abuse and related compounds. 毒物分析. 授課教師：賴滄海教授 03-28-2008. Rapid Commun. Mass Spectrom.2005;19:1332-1338. Development of a multi-target screening analysis for 301 drugs using a QTrap liquid chromatography/tandem mass spectrometry system and automated library searching.

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LC-MS of drugs of abuse and related compounds

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  1. LC-MS of drugs of abuse and related compounds 毒物分析 授課教師：賴滄海教授 03-28-2008

  2. Rapid Commun. Mass Spectrom.2005;19:1332-1338 Development of a multi-target screening analysis for 301 drugs using a QTrap liquid chromatography/tandem mass spectrometry system and automated library searching

  3. Chiral analysis of methadone and its major metabolites (EDDP and EMDP) by liquid chromatography-mass spectrometry journal of Chromatography B, 814 (2005) 315-323

  4. Doping substances • Diuretics Narcotics • β2-Blockers Cannabis • Steroids HCG Erythropoietin • Stimulants HGH Insulin, HBOC

  5. Figure 9.1Diuretics with thiazide structure are converted by hydrolysis or sulphoxidation during sample transportation, storage or preparation, which may cause analytical problems in GC-MS. Respective artefacts need to be factored into LC-MS screening

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