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Speed, Ice & Madness. A biology teacher’s guide to the stimulants in 2006. Dr Edward Ogden PSM MA MBBS BMedSc GradCertMgt FRACGP FAChAM. NIDA’s mission is to bring the power of science to bear on drug abuse and addiction. Prevalence. World wide use estimated 0.6% of population
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Speed, Ice & Madness A biology teacher’s guide to the stimulants in 2006 Dr Edward Ogden PSM MA MBBS BMedSc GradCertMgt FRACGP FAChAM
NIDA’s mission is to bring the power of science to bearon drug abuse and addiction.
Prevalence • World wide use estimated 0.6% of population • Australia has highest prevalence in the world! • 9.1 % used at some stage • 3.2% used the previous 12 months. • Average age at first use 20.8 years. • 6.6% of Australian teenagers have had experience with amphetamines • 97% if IDU’s have tried stimulants
Why worry? • Users • little understanding of effects of drug • High risk of HIV and STD • High rate of conversion from oral to IV • Unlikely to seek help • Toxicity • 25% of users are psychotic • 20% of psychoses longer than 1 month
Addictions & the reward pathway • Food • Water • Sex • Nurturing
The action of stimulants Amphetamine-type Stimulants Cocaine
Positron Emission Tomography www.drugabuse.gov
Normal On Cocaine www.drugabuse.gov
Brain on Cocaine 1-2 Min 3-4 5-6 Cocaine binding 6-7 7-8 8-9 20-30 9-10 10-20
A Brain After Cocaine Metabolic Activity
Long-term Consequences Metabolic Activity
Amygdalanot lit up Amygdalaactivated Nature Video Cocaine Video The Memory of Drugs
The good news is… Drug Abuse is apreventable behavior and Drug Addiction isatreatable disease
For More Information NIDA Public Information Office: 301-443-1124 Or www.nida.nih.gov www.drugabuse.gov National Clearinghouse on Alcohol and Drug Information (NCADI): 1-800-729-6686 www.drugabuse.gov