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The Sun Exposure and Vitamin D Supplementation (SEDS) study. Dr Sam Hoare National Centre for Epidemiology and Population Health. Vitamin D. 90% from sunlight 1 Bone health 2,3 ?CVD 4,5,6 /MS 7 /Cancer 4,5,8 /Diabetes 9 ..... Management of mild vitamin D deficiency??.
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The Sun Exposure and Vitamin D Supplementation (SEDS) study Dr Sam Hoare National Centre for Epidemiology and Population Health
Vitamin D • 90% from sunlight1 • Bone health2,3 • ?CVD4,5,6/MS7/Cancer4,5,8/Diabetes9..... • Management of mild vitamin D deficiency?? (1) Holick MF. Vitamin D: a millennium perspective. J Cell Biochem; 2003 (2) Gibson RS, Principles of Nutritional Assessment; 2005 (3) Reid, I et al. Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis. The Lancet; 2014 (4) Chowdhury, R et al. Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ; 2014 (5) Autier, P et al. Vitamin D status and ill health: a systematic review. The Lancet Diabetes & Endocrinology; 2014 (6) Rostand SG. Ultraviolet light may contribute to geographic and racial blood pressure differences. Hypertension; 1997 (7) Lucas R et al. Sun exposure and vitamin D are independent risk factors for CNS demyelination. Neurology; 2011 (8) Gandini S, et al. Meta-analysis of observational studies of serum 25-hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorectal adenoma. Int J Cancer; 2011 (9) Pittas, AG et al. The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. Journal of Clinical Endocrinology & Metabolism; 2007
Vitamin D deficiency in Australia “Around four million Australian adults……. just under one in every four…. were Vitamin D deficient in 2011–12” (Australian Bureau of Statistics - 15thApril 2014 www.abs.gov.au/australianhealthsurvey) (Vitamin D deficiency < 50 nmol/L)
Seasonal and regional variation in Vitamin D deficiency Winter 2011/12 Summer 2011/12
The SEDS Study • Are there non-vitamin D benefits of sun exposure? • Is it possible to increase your vitamin D through safe sun exposure?
The SEDS study • Australia-wide randomized controlled trial • Currently recruiting • Participants aged 18-64 yrs AND 25(OH)D 40-60nmol/L AND not taking Vit D supplements • 1 year intervention
How you can refer a patient (it’s very easy!) • Recruitment through General Practice • www.sedsstudy.org • info@sedsstudy.org • Tel – 1800 73 2223 • Fax – 02 6125 5614 • Self-referral – via website, phone or email