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GOAL NCI-DESIGNATION OF STANFORD UNIVERSITY AS A COMPREHENSIVE CANCER CENTER

GOAL NCI-DESIGNATION OF STANFORD UNIVERSITY AS A COMPREHENSIVE CANCER CENTER. Email: kgblume @stanford.edu Phone: 3-0822 Fax: 8-4418. NCI-DESIGNATED CANCER CENTERS IN THE USA/CA. USA CA Basic Research Cancer Centers 8 2

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GOAL NCI-DESIGNATION OF STANFORD UNIVERSITY AS A COMPREHENSIVE CANCER CENTER

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  1. GOALNCI-DESIGNATION OF STANFORD UNIVERSITYAS A COMPREHENSIVE CANCER CENTER Email: kgblume @stanford.edu Phone: 3-0822 Fax: 8-4418

  2. NCI-DESIGNATED CANCER CENTERS IN THE USA/CA USACA Basic Research Cancer Centers 8 2 Clinical Cancer Centers 15 1 Comprehensive Cancer Centers 396 62 9

  3. A Comprehensive Cancer Center has reasonable depth and breadth of research activities in each of three major areas: basic, clinical, and prevention, control, behavioral and population-based research and exhibits a strong body of interactive research that bridges these scientific areas.In order to receive recognition as an NCI-designated Comprehensive Cancer Center the center must meet the above scientific requirements as well as provide outreach, education and information on cancer to the community it serves.

  4. In the area of clinical cancer research, a comprehensive cancer center is encouraged to initiate and conduct early phase, innovative clinical trials and to participate in the NCI’s cooperative group system by providing leadership and accruing patients to trials.

  5. All NCI-designated cancer centers (basic, clinical or comprehensive) satisfy the following six characteristics: 1. CANCER FOCUS 2. INSTITUTIONAL COMMITMENT 3. CENTER DIRECTOR 4. ORGANIZATIONAL CAPABILITIES 5. FACILITIES 6. INTERDISCIPLINARY COORDINATION AND COLLABORATION

  6. CANCER CENTER SUPPORT GRANT (P30) APPLICATION I.Programs in Basic Cancer ResearchProgram Leaders A. Cancer/Stem Cell Biology Research I. Weissman B. Genomics & Proteomics Research P. Brown C. Radiation Biology & DNA Repair Research A. Giaccia D. Cancer Biology & Cell Cycle Regulation Research J. Lipsick E. Cancer Immunology Research E. Engleman F. Cancer Imaging Research S. Gambhir G. Biomedical Informatics & Biomedical Computation Research M. Musen II. Programs in Translational/Clinical Cancer Research A. Pediatric Cancer Research Program M. Cleary B. Lymphoma and Hodgkin’s Disease R. Levy C. Hematopoietic Cell Transplantation: Biology & Therapy for Cancer R. Negrin D. Genetics of Epithelial Tumors (Skin, Breast, GI, GU, GYN): J. Ford From Genomic Profiling to Clinical Counseling E. Cancer Pharmacology/Experimental Therapeutics B. Sikic III. Program in Population Sciences and Education A. Cancer Epidemiology/ Cancer Control D. West Patient Education/ Outcomes Research

  7. CANCER CENTER SUPPORT GRANT (P30) APPLICATIONResearch Programs I. Programs in Basic Cancer Research A. Cancer/Stem Cell Biology Research I. Weissman, R. Nusse, J. Shizuru, T. Cao, M. van de Rijn, G. Harsh, S. Skirboll, T. Palmer, V. Tse, S. Kim, N. Teng, A. Hussain, L. Giudice, M. Fuller, M. Scott B. Genomics & Proteomics Research P. Brown, G. Nolan, J. Pollack, M. van de Rijn, S. Jeffrey, S. So, J. Brooks, P. Utz, G. Chu, M. Bogyo, R. Tibshirani, V. Pande, T. Hastie, R. Zare C. Radiation Biology & DNA Repair Research A. Giaccia, M. Brown, A. Boyer, L. Xing, G. Chu, J. Ford, S. Knox, N. Denko, Q. Le, A. Koong, R. Tibshirani, Q. Lu, D. Bouley, P. Hanawalt D. Cancer Biology & Cell Cycle Regulation Research J. Lipsick, P. Jackson, L. Boxer, D. Felsher, T. Wang, J. Axelrod, J. Sage, D. Feldman, M. Powell, S. Artandi, M. Cleary, J. Crabtree, L. Attardi, C. Cartwright, G. Fang, T. Stearns, M. Simon E. Cancer Immunology Research E. Engleman, M. Davis, R. Levy, E. Butcher, R. Negrin, P. Parham, W. Song, A. Krensky, G. Nolan, G. Fathman, J. Parnes, N. Teng, P. Lee, S. Galli, P. Jones F. Cancer Cell & Tissue Imaging Research S. Gambhir, C. Contag, G. Glover, B. Daniel, N. Pelc, R. Negrin, S. Plevritis, S. Napel, G. Glaser, F. Sommer, D. Bouley, D. Nishimura, J. Pauly G. Biomedical Informatics & M. Musen, R. Altman, H. Lowe, R. Tibshirani, R. Olshen, N. Risch, S. Plevritis, S. Napel, A. Sidow, C. Ball, G. Sherlock, Biomedical Computation Research R. Carlson, T. Lai,V. Pande, M. Feldman, S. Delp, I. Johnstone II. Programs in Translational/Clinical Cancer Research A. Pediatric Cancer Research Program M. Cleary, M. Link, A. Krensky, G. Dahl, L. Boxer, B. Fine, N. Marina, D. Felsher, N. Lacayo, S. Donaldson, H. Cohen B. Lymphoma and Hodgkin’s Disease R. Levy, S. Horning, L. Boxer, M. Cleary, S. Levy, G. Nolan, D. Felsher, P. Brown, S. Falkow, S. Hancock,, R. Hoppe, Y. Kim, R. Tibshirani, R. Warnke, J. Zehnder, S. Glaser, J. Swartz C. Hematopoietic Cell Transplantation: R. Negrin, S. Horning, J. Shizuru, I. Weissman, S. Strober, R. Levy, E. Engleman, P. Parham, A. Arvin, E. Mocarski, Biology & Therapy for Cancer J. Brown, W. Brown, C. Contag, J. Zehnde D. Genetics of Epithelial Tumors J. Ford, R. Davis, H. Ji, A. Oro, P. Khavari, P. Marinkovich, A. Whittemore, S. Jeffrey, I. Wapnir, R. Carlson, G. Rosen, (Skin, Breast, Lung, GI, GU, GYN S. Cohen, J. Pollack, J. Brooks, D. Peehl, D. Feldman, Z. Sun, N. Teng, A. Hussain, J. Mollick, C. Cartwright, A. Lowe, J. Norton, J. Axelrod E. Cancer Pharmacology/Experimental Therapeutics B. Sikic, C. Kuo, R. Roth, R. Altman, K. Cimprich, H. Blau, T. Meyer, D. Yean, D. Ikeda, J. Chen, D. Mochly-Rosen, M. Bogyo, P. Wender, S. Boxer, C. Khosla, T. Wandless III. Program in Population Sciences and Education A. Cancer Epidemiology/Outcomes Research D. West & NCCC, A. Whittemore, J. Parsonnet, S. So, N. Risch, L. Nelson, A. King, J. Killen, D. Spiegel, S. Plevritis, Patient Information - Education/Control R. Carlson, M. Gould, S. Fortman, T. Robinson, C. Taylor, M. Stefanik, L. Huffman, L. Crawley

  8. Shared Resources (“Cores”) LeadersA. Biostatistics for Clinical Cancer Research R. Tibshirani(Acting), T. LaiB. Clinical Trials Office B. SikicC. Informatics Core H. LoweD. General & Specialized Animal Colonies R. Tolvani, M. GarciaE. Cell & Tissue Distribution J. Pollack, J. Norton, D. PeehlF. High TP DNA Sequencing/SNIP R. Davis, P. Oefner, R. MyersG. Cancer Imaging C. Contag, S. Gambhir, B. DanielH. Confocal & Immunoelectron Microscopy S. Smith, J. MulhollandI. Flow Cytometry G. Nolan, L. HerzenbergJ. Transgenic and Knock-out Mice M. Cleary, D. Felsher, Y. Chen.TsaiK. DNA-Micro Array including Database G. Sherlock, M. Fero, C. BallL. Proteomics P. Jackson, G. NolanM. Translational/Clinical Research Resource G. Fisher

  9. INVESTIGATORS IN CLINICAL CANCER RESEARCH/TRANSLATIONAL MEDICINE BMT L. Johnston Urology J. Presti G. Laport R. Lowsky I.R. S. Kee K. Stockerl-Goldstein M. Razavi M. Stuart D. Sze Hematology S. Coutre Radiology R. Birdwell P. Greenberg L. Chao T. Desser Med. Onc. R. Advani G. Glaser G. Fisher D. Ikeda C. Jacobs B. Jeffrey H. Pinto S. Srinivas Nuc. Med M. Goris Rad. Onc. S. Donaldson R. McDougall I. Gibbs R. Hoppe Pediatrics M. Link C. King N. Marina D. Kapp C. Twist S. Knox Neuro-Onc. P. Fisher Surg. Onc. F. Dirbas L. Recht W. Fee R. Greco Dermatology G. Hayes D. Johnson S. Swetter M. Kaplan M. Welton GI (Med) J. Van Dam R. Whyte

  10. External Advisory Board M. Abeloff, J. Hopkins E. Benz, DFCI J. Glick, Penn E. Harlow, Harvard L. Hartwell, FHCRC J. Niederhuber, Wisconsin J. Niland, City of Hope L. Strong, Anderson M. Waldinger, U. Michigan

  11. TIMELINE FOR CCSG February 1, 2003 Start of Planning Process March 18, 2003 Dean Pizzo at NCI; Meets with NCI Director, A. von Eschenbach, M.D. April 8, 2003 Faculty Town Hall Meeting re. CCC July 24, 2003 Start of National Search for: Director of CCC/PI of CCSG/Associate Director of CSCI October 22, 2003 Dean meets with Leaders of Programs and Cores October 23 and 24, 2003 Visit of first candidate for the position of Director October 26, 2003 KGB meets NCI Program Director, Linda Weiss, Ph.D. November 4, 2003 Dean meets NCI Program Director, Linda Weiss, Ph.D. November 15, 2003 On Campus Retreat of all Investigators (BioX) January 5 and 6, 2004 Visit of second candidate for the position of Director March 8 and 9, 2004 Visit of third candidate for the position of Director March 19, 2004 Review by External Advisory Board Members April 19, 2004 (t) Dean meets Karen Antman, M.D., NCI Director for Cancer Centers May 12, 2004 (t) Visit of Linda Weiss, Ph.D. to Stanford University October 1, 2004 CCSG Application to NCI (Request for three years of support) January/February 2005 Site Visit by NCI Staff and Review Panel Members July 1, 2005 Hopefully: Begin of NCI Funding

  12. David Nathan and Edward J. Benz, Jr. “Comprehensive Cancer Centers and the War on Cancer” Nature, December 2001 Pages 240-245

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