TF + S

1. Full model with mRNA – F1 tf mRNA_TF ka TF|S TF + S kd TF|S phzM phzS mRNA_PhzM mRNA_PhzS PhzM PhzS PCA MPCAB PYO

2. Full model without mRNA – F2 tf ka TF|S TF + S kd TF|S phzM phzS PhzM PhzS PCA MPCAB PYO

3. Positive Feedback loop with mRNA tf mRNA ka TF|S TF + S kd TF|S tf phzM phzS mRNA_PhzM mRNA_PhzS PhzM PhzS PCA MPCAB PYO

4. Positive feedback without mRNA – F3 tf ka TF|S TF + S kd TF|S tf phzM phzS PhzM PhzS PCA MPCAB PYO

5. Constitutive expression of PhzM without mRNA – F4 phzM tf PhzM PCA MPCAB PYO ka TF + S TF|S kd TF|S phzS PhzS

6. Constitutive expression of phzm with mRNA phzM tf mRNA_PhzM mRNA_TF PhzM PCA MPCAB PYO ka TF + S TF|S kd TF|S phzS mRNA_PhzS PhzS

7. Iteration 2 - Full model without MRNA and MPCAB - F5 tf ka TF|S TF + S kd TF|S phzM / phzS PhzM / PhzS PCA PYO

8. phzM Feedback loop for phzM - Karolois tf PhzM PCA MPCAB PYO ka TF + S TF|S kd phzM TF|S phzS PhzS

9. Iteration 2 – F6 tf ka TF|S TF + S kd TF|S tf phzM / phzS PhzM / PhzS PCA PYO