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Perinatal Pathology: A Review

Perinatal Pathology: A Review. Dr G Mortimer UCHGalway. Totals 2003. Mothers: 1,203P 1,941M = 3,144 Babies: 1,223P 1,976M = 3,199 Singletons: 1,183P 1,907M = 3,090 Twins: 20P 33M = 53 Triplets: 0P 1M = 1.

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Perinatal Pathology: A Review

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  1. Perinatal Pathology:A Review Dr G Mortimer UCHGalway

  2. Totals 2003 • Mothers: 1,203P 1,941M = 3,144 • Babies: 1,223P 1,976M = 3,199 • Singletons: 1,183P 1,907M = 3,090 • Twins: 20P 33M = 53 • Triplets: 0P 1M = 1

  3. Total Babies • 1999: 2,704 • 2000: 2,830 • 2001: 3,001 • 2002: 3,218 • 2003: 3,199

  4. Multiple Births • 1999: Twins 48, Triplets 6; Total = 54 • 2000: Twins 45, Triplets 0; Total = 45 • 2001: Twins 42, Triplets 1; Total = 43 • 2002: Twins 56, Triplets 4; Total = 60 • 2003: Twins 53, Triplets 1; Total = 54 • 2004: Twins 61, Triplets 0; Total = 61

  5. Non-National Deliveries • 1999: 18 0.6% • 2000: 59 2.0% • 2001: 202 6.8% • 2002: 361 11.5% • 2003: 364 11.5%

  6. Perinatal Mortality Rates • 1999 2000 2001 2002 2003 • Stillbirths 0.5% 0.8% 0.7% 0.5% 0.7% • NND 0.4% 0.3% 0.2% 0.4% 0.3% • Total Rate 0.9% 1.1% 0.9% 0.9% 1.0%

  7. Perinatal Loss 2003 • Total = 31 • 21 Antepartum Stillbirths • 10 Neonatal Deaths

  8. Perinatal Deaths • Autopsy No Autopsy • All: 31 17 (55%) 14 (45%) • NND: 10 3 (30%) 7 (70%) • SB: 21 14 (66%) 7 (33%)

  9. Perinatal Deaths 2003 • Stillbirths: 9P 12M = 21 (0.7%) • Early NND: 6P 4M = 10 (0.3%) • Total: 15P 16M = 31 (1.0%)

  10. Causes Antepartum Deaths Prims Multips Total Unexplained 3 9 12 Abruptio 2 1 3 TTS 2 0 2 Cord Accident 1 1 2 IUGR 0 1 1 Malformation 1 0 1

  11. Stillbirths UCHG 1973-1992 • 1973-82 1983-92 • Congenital anomalies 62 31 • Asphyxia 75 20 • PET 41 5 • Maternal disease 25 7 • IUGR 55 27 • Unexplained 33 60 • Other 30 4 • Total 321 154

  12. Stillbirth Rate/1000 UCHG 1973-1992 • 1973-82 1983-92 • Congenital anomalies 2.3 1.2 • Asphyxia 2.7 0.8 • PET 1.4 0.2 • Maternal disease 0.9 0.3 • IUGR 2.0 1.0 • Unexplained 1.2 2.37 • Other 1.1 0.15 • Total 11.7 5.98

  13. Causes Neonatal Deaths • Prims Multips Total • Malformations 2 1 3 • Prematurity 3 0 3 • Infection 0 1 1 • TTS 0 2 2 • Abruptio 1 0 1

  14. Autopsies 2004 • Total : 14 • Neonates : 5 • Stillbirths : 9

  15. Neonatal Autopsies 2004 • Twins TTS MoDi Early • T2 Premature DiDi/Infarct Early • RDS Late • Congenital Anomaly Early

  16. Stillbirth Autopsies 2004 • Unexplained 7 • Congenital Anomaly 2

  17. Unexplained Stillbirths 2004 (8) • Twins TTS MoDi Infarction • T1 DiDi Infarction • Acute chorioamnionitis + Infarction • Acute chorioamnionitis + SROM • Infarct + PET-type maternal vasculopathy

  18. Sudden Infant Death Syndrome 2004 • 2 Cases

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