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  1. Patient-related predictors of short and long term implant failure after primary total hip arthroplastyA nationwide Danish follow-up study with 36 984 patientsAlma B. Pedersen1,2, Søren P. Johnsen2, Søren Overgaard3, Kjeld Søballe1, Henrik T. Sørensen2 and Ulf Lucht11Department of Orthopaedics, Aarhus University Hospital, Denmark. 2Department of Clinical Epidemiology, Aarhus University Hospital, Denmark. 3Department of Orthopaedics, Odense University Hospital, Denmark Aim Results Conclusion We examined the association between patient-related factors, including gender, age, primary diagnosis, and comorbidity and the risk of short and long term implant failure after primary total hip arthroplasty (THA). Male gender or high comorbidity index are time-independent predictors for THA failure, and remained a strong predictive factors for failure irrespective of time window of follow-up. Age and primary diagnoses were identified as time-dependent predictors for THA failure. Thus, in the time window from 0-30 days after primary THA, age 80 years and more, as well as diagnoses sequelae after trauma, avascular necrosis, and paediatric diseases, were found to be predictors for THA failure. In the time interval from 6 months to 8.6 years after surgery, age between 10-49 and 50-59 years were able to predict THA failure, whereas neither of diagnoses could be identify as predictor in this time window. Predictors for implant failure from any causes in three time periods after primary total hip arthroplasty. High comorbidity index Male Methods We identified patients with primary THA registered in the Danish Hip Arthroplasty Registry between 1 January 1995 and 31 December 2002 (n=36,984). Separate analyses were done for 3 follow-up windows, including 0 to 30 days (median follow-up of 29.8 days), 31 day to 6 months (median follow-up of 4.9 months), and 6 months to 8.6 years after primary THA (median follow-up of 3.5 years). Data on all changes in vital status for each patient and comorbidity were obtained from the Central Personal Registry and the Danish National Registry of Patients, respectively. The outcome was defined as time to failure (revision). Cox regression analyses were used to estimate the Relative Risk for failure (RR) for the possible predictors adjusted for other covariates. Diagnoses Age Correspondence to: Danish Hip Arthroplasty Registry, 10 years jubilee 1995-2005 www.dhr.dk Alma Becic Pedersen, MD, PhD (abp@dce.au.dk or abp@ag.aaa.dk)

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