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Do Magic Mushrooms have medicinal value?. Joshua Root. Psilocybin Facts. Contained in many different mushrooms. Originated in East Africa serotonin (5-HT)-2A/2C receptor agonist ILLEGAL!. Effects. Psilocin Duration of 3-8 hours. Effects Continued. Physical effects
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Do Magic Mushrooms have medicinal value? Joshua Root
Psilocybin Facts • Contained in many different mushrooms. • Originated in East Africa • serotonin (5-HT)-2A/2C receptor agonist • ILLEGAL!
Effects • Psilocin • Duration of 3-8 hours
Effects Continued • Physical effects • Increase in heart rate • Elevated blood pressure • Dilated Pupil • Nausea • Coldness and weakness in limbs
Effects Continued • Emotional effects • Strongly dependent on setting • Mood swings • Exaggeration of mood at ingestion
Effects Continued • Sensory effects • Visual • Auditory • Synthesia • stimulation of one sensory or cognitive pathway leads to automatic, involuntary experiences in a second sensory or cognitive pathway
Proposed Medicinal Uses • Psychotherapy • 1950’s • Modern proposals • OCD • Cluster Headaches • Body dysmorphic disorder
Treatment of OCD • OCD • 4th most commonly diagnosed psychiatric disorder • Complications • Depression, suicidal tendencies, panic, substance abuse, and interpersonal difficulties • Dysregulation of Serotonin • 5-HT reuptake inhibitors
OCD Treatment Findings • Dr. Francisco Moreno • Completely removed symptoms • 4-24 hours • Jeremy • Fear of contamination • Symptoms relieved
Treatment of Cluster Headaches • Triggered by a few different causes • Interruption of sleep pattern, certain medication, abnormal hormone levels, and heavy smoking and drinking alcohol • Results • 53 participants • 85% aborted attack • 95% reported extension in remission • 42% benefited from sub hallucagenic doses
Treatment of Body Dysmorphic Disorder • Mr. A • Relieved symptoms • Mrs. B • Relieved symptoms
Critiques and Comments • Duration of positive results • Not a drug that can be used all the time • Less toxic than aspirin
http://www.doitnow.org/pages/132.html • http://en.wikipedia.org/wiki/Psilocybin_mushrooms#Medicinal_use • http://www.maps.org/research/psilo/azproto.html • http://www.ncbi.nlm.nih.gov/pubmed/16801660 • http://en.wikipedia.org/wiki/Body_dysmorphic_disorder • http://www.msnbc.msn.com/id/16304852/ • http://news.bbc.co.uk/2/hi/health/6210694.stm • http://www.shroomery.org/6233/Psychedelic-Mushrooms-Just-another-Drug-or-a-Powerful-Medicine