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Supplementary Figure 1 Supplementary figure 1. Relative ovarian expression of hypoxia-inducible factor (HIF)-1α and HIF-2α mRNAs in croaker at the time of the November sampling. N=6. A nested ANOVA analysis indicates HIF-1α and HIF-2α mRNA levels in croaker from the normoxic sites are significantly different from those in fish from the hypoxic sites (***p<0.001). Individual site differences identified with a multiple range test, Fisher’s PLSD, are indicated with different letters ( p<0.05).