1 / 11

Isotope R&D Facility

This proposal outlines the need for a new Isotope R&D Facility as an addition to the HRIBF driver upgrade at ORNL. The facility would support a sustained research program in isotope production, offering a substantial allocation of beam time and shared operational costs. The estimated total incremental cost is 7-10M$, with little impact on the HRIBF mission or flexibility.

patricaa
Download Presentation

Isotope R&D Facility

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Isotope R&D Facility A proposed addition to the HRIBF driver upgrade Mike Saltmarsh HRIBF Users’ Meeting Nov 13th 2009

  2. Proposed Isotope Production R&D FacilityNational Context • There is a national need for a reinvigorated DOE isotope program – selected recommendations from NSAC report • “Support a sustained research program…. In the production and supply of isotopes….” • “Investment in new production capabilities” • “Investment in workforce development”

  3. Shared use of the C70 is unusually attractive • A substantial allocation of beam time to the isotope program would be available ( ~ 4500h/yr) • Little or no impact on the HRIBF mission or flexibility would be incurred • Concurrent construction of the isotope facility would not significantly impact the C70 upgrade construction • ORNL already has all the required isotope infrastructure from production through transportation • The incremental capital cost to the isotope program would be modest (7-10M$) • The opportunity to share operations costs would benefit both programs

  4. Elements of the proposed facility • Dedicated isotope target vault • Two beamlines from the C70 to the isotope vault • Two target stations, one a commercially available standard, the other compatible with the BNL/LANL target systems • Systems for remote transfer of the target modules from target station to transfer cell. • A transfer cell to package irradiated modules for transfer to the ORNL hot cells Items in red are part of the isotope facility Currently estimated total incremental cost is 7-10 M$

  5. Maximum power dissipation of target assembly (on blank copper target): 12 kW Beam profile on target: Gaussian 6 mm FWHM, rotated to uniform flat beam Angle of target face to beam: 6 degrees IBA Solid Target System Specifications

  6. Beams available from the C70

  7. Important Characteristics of the C70 and it’s anticipated operating regimes • Very high reliability (~ 95% for commercial C30) • Expectations for the HRIBF operating environment ~ 6600h/yr of extracted beam availability. 42 weeks, 156 h/week, 7 day operation. • Dual extraction capability for negative ion beams • HRIBF needs for RIB production ~ 4000 h/yr • Most RIB production (3000h/yr) requires the full energy proton beam at intensities 50 mA and higher • Allows simultaneous use of 70 MeV protons by isotope program. Independent intensity control (within limits) • HRIBF operation includes periods of days-weeks when C70 beams not required • 1500-2000 h/yr of dedicated beams (including alphas) available for the isotope program

  8. Elements of the Proposed Isotope Program would address many of the needs identified in the NSAC report • Radioisotope production R&D • New production regimes, eg for 225Ac • Excitation functions, thick target yields • Nuclear and radiochemistry • High power target design • Radioisotope Production • Research isotopes, eg 211At, 68Ge, 7Be • Commercial Isotopes, eg 82Sr, 68Ge • Education and Training

  9. Production R&D example • Short-lived (46 m) alpha emitter 213Bi offer great promise for radioimmunotherapy • Attach radionuclide to suitable antibody • Antibody preferentially attaches to tumor cell • Radiation delivered within ~100m of tumor cell, not elsewhere • Supplies are limited, hindering clinical trials • Currently source is 233U - 229 Th (7880y) - 225Ac (10d) as a generator for 213Bi • R&D required to investigate other possible production methods • Funded proposal to look at excitation functions and thick target yields for protons on 230Th and 232Th targets* at HRIBF • * garlandma@ornl.gov , stracenerdw@ornl.gov

  10. ORNL Infrastructure Available for Education and Training • Production R&D • Seek University partnerships • Training programs using ORNL facilities • Production facilities • Hot cells for target processing • Radiochemistry labs • Animal facilities • Transportation • Workshops • Workshop on next generation of radiochemists planned for spring 2010

  11. Shared use of the C70 is unusually attractive • A substantial allocation of beam time to the isotope program would be available ( ~ 4500h/yr) • Little or no impact on the HRIBF mission or flexibility would be incurred • Concurrent construction of the isotope facility would not significantly impact the C70 upgrade construction • ORNL already has all the required isotope infrastructure from production through transportation • The incremental capital cost to the isotope program would be modest (7-10M$) • The opportunity to share operations costs would benefit both programs

More Related