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Morphology. TinyNonliving (do not grow, move or respire)Smaller than bacteriaReproduce inside a living cell called (host cell). Naming of Viruses. Disease they causeRabies virusPolio virus. . Rabies virus. Polio virus. Organ or tissue they infectAdenovirus Attacks adenoid tissue at the back of the throat.
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1. Viruses
3. Naming of Viruses Disease they cause
Rabies virus
Polio virus
4. Organ or tissue they infect
Adenovirus
Attacks adenoid tissue at the back of the throat
5. Bacteriophage
A virus that infects bacteria
6. Structure Inner core
Contains DNA or RNA (never both)
Nucleic acid contains genes that codes only for making DNA copies and nothing else
Capsid
The protein shell that encloses the nuclei acid
Envelope
Found in large viruses
8. Shapes of Viruses Depends on the arrangement of the proteins on capsid (viral coat)
Plays a role in the infection process
9. Polyhedral
Looks like small crystal
Most have 20 sides
Polio virus and T4 bacteriophage
Cylindrical
Tobacco mosaic viruses
Enveloped viruses
Envelope studded with projections
HIV and influenza virus
10. Polyhedral
11. Cylindrical
12. Enveloped viruses
13. How do we get infected? Viruses have different proteins on the surface
Proteins interact with specific receptor cells on their host’s plasma membrane
Attachment of virus to host cell is specific
Most can only enter and reproduce in a few kind of cells
Some viruses are cell-specific
Polio viruses can only infect nerve cells in humans
15. Lytic Cycle DNA injected into cell
Transcription/translation of 100 viral genes
DNase chops up host DNA
DNA modification protects viral DNA
Virus undergoes self-assembly
Lysozyme chews hole in cell wall ? host cell burst
16. Lytic cycle
17. Lysogenic cycle Viral nucleic acid is inserted into genetic material of host
Forms provirus
Provirus – virus formed when viral DNA is inserted into the host cell chromosome
Host replicates with it
Can go undetected in this cycle for years
Eventually enter the lytic cycle and kills the host cell
18. Lysogenic cycle
19. Lysogenic viruses
20. Retroviruses HIV
RNA as nucleic acid
Injects nuclei acid and reverse transcriptase
Reverse transcriptase - enzyme that copies viral RNA into DNA Reverse transcriptase is a common name for an enzyme that functions as an RNA-dependent DNA polymerase. They are encoded by retroviruses, where they copy the viral RNA genome into DNA prior to its integration into host cells
Reverse transcriptase is a common name for an enzyme that functions as an RNA-dependent DNA polymerase. They are encoded by retroviruses, where they copy the viral RNA genome into DNA prior to its integration into host cells
21. RNA lytic viruses Nucleic acid is RNA but not reverse transcriptase
Can only copy RNA to DNA in absence of RT
Follow the lytic cycle
22. Plant viruses Tobacco mosaic virus
First virus identified
May cause distinct coloration or variegation in flowers
Not always fatal of harmful
Attacks tomato plants