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Oracle Health Sciences Global Business Unit Strategy

Oracle Health Sciences Global Business Unit Strategy. Steve Rosenberg Senior Vice President and General Manager Oracle Health Sciences Global Business Unit. Clinical R&D - What hasn’t Changed…. Improved Outcomes & Care. Greater Safety. Reduced Costs. Streamlined R&D.

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Oracle Health Sciences Global Business Unit Strategy

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  1. Oracle Health Sciences Global Business Unit Strategy Steve Rosenberg Senior Vice President and General Manager Oracle Health Sciences Global Business Unit

  2. Clinical R&D - What hasn’t Changed… • Improved Outcomes & Care • Greater Safety • Reduced Costs • Streamlined R&D

  3. Clinical R&D - What Continues to Change … • Science & Technology • Clinical R&D Process • Patient Engagement • Clinical R&D Landscape

  4. Oracle Health Sciences • Accelerate clinical development • Support entire drug safety lifecycle • Enable clinical data aggregation Life Sciences • Power enterprise healthcare analytics • Enable provider/payer integration • Drive personalized medicine • Healthcare • The movement from clinical research to clinical care • Develop collaboration networks for providersand life sciences companies • Continuum

  5. Life Sciences

  6. Optimizing Clinical Research & Development Analytics and Insights Planning & Budgeting Trial Management & Monitoring Randomization & Trial Supply Management Comprehensive Electronic Data Capture Clinical Data Aggregation& Reporting Signal Detection Safety Lifecycle HEALTH SCIENCES CLOUD

  7. Oracle Life Sciences Broadest, best-of-breed applications Focus on integration The highest standards of scalability, security, and privacy

  8. Recent Oracle Life Sciences Innovations MOBILITYINFORM, CRA & ANALYTICS KEY PRODUCT & THIRD PARTY INTEGRATIONS CLINICAL MONITORING CLOUD RISK BASED MONITORING DATA MANAGEMENTWORKBENCH REAL-WORLD SAFETY SURVEILLANCE & COMPARATIVE EFFECTIVENESS INFORM ADVANCED MOLECULAR ANALYTICS MEDICATION ADHERENCE (PROTEUS)

  9. Medication Adherence • FDA-approved ingestible sensors • Captures the body’s physiologic responses and behaviors • Sends digital health information to a mobile app • Oracle’s clinical trial applications customers have exclusive access to real-time data on therapeutic use 8

  10. Medication Adherence • Medication compliance insight • Better dose selection • Fewer Phase III failures • Improved drug safety 9

  11. DEEP-ROOTED COMMITMENT TO DRIVING CLINICAL R&D PROCESS OPTIMIZATION AND ANALYTIC INSIGHTS

  12. Healthcare

  13. Healthcare Providers are Facing: Changing business models and risk shifting Margin pressure – cost, revenue, and volume Immediate Focus: • Operational effectiveness • Risk-based revenue Consolidation pressure Aging population and management of chronic diseases Evolves Over Time: Increased complexity in regulation • Patient engagement and compliance • Care coordination • Population health • Precision medicine

  14. Powering Enterprise Healthcare Analytics Oracle Enterprise Healthcare Analytics Enabling Value Through Multiple & Disparate Data Sources Normalize Aggregate Analyze • Clinical • Finance • Human Resources • Supply Chain • Claims • Genomics • Research • Clinical Trials • 3rd Party Data Client Developed Apps Comprehensive Healthcare Data Model Third Party Apps Combines Clinical and OMICS Data Oracle Apps Data Governance Productized Data Loaders Application Choice Leverages Oracle Technology

  15. Continuum

  16. Harnessing Big Data for Life Sciences & Healthcare Delivers: Biomarker discovery Protocol validation and patient recruitment Patient stratification Safety and comparative effectiveness Population health Precision medicine • Volume and availability of data continues to increase • Data will have various strengths and significance • Velocity of data is coming in faster than ever before • Who better than Oracle to attack this? Genomics Petabytes of information Real-World Data Variety of data sources Sensors Velocity of real-time data

  17. Harnessing Big Data for Life Sciences & Healthcare Delivers: Biomarker discovery Protocol validation and patient recruitment Patient stratification Safety and comparative effectiveness Population health Precision medicine Genomics Petabytes of information Oracle Health Sciences Real-World Data Variety of data sources Sensors Velocity of real-time data

  18. Effectiveness of Most Drugs Cost of Ineffectivenessto Healthcare System Major Drug Drug Effectiveness Hypertension Drugs ACE Inhibitors 10-30% $390 million – $1.2 billion Heart Failure Drugs Beta Blockers 15-25% $345 million – $575 million Anti Depressant Drugs SSRIs 20-50% $2.3 billion – $5.8 billion Cholesterol Drugs Statins 30-70% $3.8 billion – $8.8 billion Asthma Drugs Beta-2-agonists 40-70% $560 million – $1.0 billion Source: The Personalized Medicine Coalition

  19. Improving Population Health and Patient Outcomes CURRENT TRANSFORMATION • Targeted treatments • More effective trials • Faster time to market • Improved safety • Dramatically lower costs Combining Clinical and OMICS data

  20. Cloud-Based Collaborative R&D Oracle Health Sciences Network Healthcare Provider Participants Life Sciences Participants • While Ensuring: • Full control of de-identified data • Protection of Institutional IP • Respect for patient consent • Full HIPAA compliance Network Participants Include:

  21. Why Oracle Health Sciences? INDUSTRIAL STRENGTH CAPABILITY BEST-OF-BREED TECHNOLOGY UNMATCHED DOMAIN EXPERTISE INNOVATION & TRANSFORMATION DEEP & BROAD DATA MANAGEMENT COMMITTED INVESTMENT IN LIFE SCIENCES & HEALTHCARE

  22. FROM PIPELINE TO PATIENT OPTIMIZINGAND TRANSFORMING LIFE SCIENCES AND HEALTHCARE

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