Portable Heart Attack Detector (PHAD) Characterization Presentation

1. Supervisor Daniel Alkalay System architectures Nir Gluzman Alexei Iolin Technion – Israel Institute of Technology Department of Electrical Engineering High-Speed Digital Systems Lab Portable HeartAttack Detector(PHAD)Characterization Presentation April 6, 2005

2. Did You Know? • More than 1.2 million Americans will suffer a heart attack, where about 502,000 of these people will die! 340,000 of them in an ER or BEFORE they reach a hospital. • Surviving a heart attack depends on the treatment that is given within the first hour of the heart attack. • Most common reason for treatment delay is patient unawareness. Source: American Heart Association, 2004 estimation.

3. The Solution Portable HeartAttack Detector

4. AGENDA • Medical Background • Project Objective • System Block Diagram • NI/FPGA – Pros & Cons • Project Time-Table • Summary

5. Medical Background ECG = Electrocardiogram • Recording of heart’s electrical activity. • Measures rate and regularity. • Used to diagnose diseases.

6. R T P Q S Medical Background (cont.) Basic ECG complex

7. Medical Background (cont.) Heart attack(Myocardial Infarction) • An event that results in permanent damage to the heart. • myocardium = heart muscle. • infarct = die. • Q-waves and inverted T-waves are two diagnostic wave forms seen in old heart attacks and new heart attacks respectively.

8. ST-Elevation (STEMI) • Elevation of ST-segment relative to PR or TP segment. • ST-elevation is a sign for coming heart attack (acute myocardial infarction). • Short PR interval - very difficult for computer algorithms to find the isoelectric reference level.

9. PXI-7831R Project Objective • Develop a system that measures and displays RR-rate, ST-elevation and alert to wide-QRS. • Implement the system on National-Instrument(*)Real-Time FPGA development environment using LabView graphical language. (*) website: http://ni.com

10. Biosensors A/D interface Detection of ECG characteristic pointswith filter-bank Detection of RR-rate, ST-elevation, wide-QRS Abnormalitiesalert System Block Diagram

11. Filter-Bank Block Diagram • Input signal is sampled at 360Hz.

12. R-detection RR-rate &wide-QRS detection DecomposedSignal ST-elevation detection Abnormalities detection(cont.)

13. Abnormalities detection(cont.) R-detection RR-rate & QRS-duration ST-elevation

14. NI/FPGA – Pros & Cons Pros • Rapid prototype system. • Dedicated hardware and software. Cons • NI development environment is non-conventional – design extraction to other non NI/FPGA environments is NOT possible. • VHDL code is hidden from user.

15. Subject Time period (weeks) Study of NI/FPGA & LabView development environment 3 Implementation 5 Design verification 2 Limited clinical experiments (optional) 1 Final report and project summary 2 Project Time-Table

16. Summary • Patient need for PHAD. • Detailed design of the system. • Pros & cons of NI development environment.

17. Questions?