Portable Pathogen Detector

1. Classifier Image Sample M M Reporter Image Laser Laser L DC DC M F CCD Camera Classifiers Reporter Portable Pathogen Detector Image bead and reporter fluorescence, perform image analysis, and score results Hand-held instrument Immunoassay using optically encoded beads for multiplex capability To detect anthrax spores, MDRTB, smallpox virus, toxins, etc.

2. Tissue Engineering is a hot new fieldScience, Feb 8, 2002, p1009 • Griffith and Naughton of MIT….. “Tissue engineering can be used to restore, maintain or enhance tissues and organs. The potential impact of this field, however, is far broader – in the future, engineered tissues could reduce the need for organ replacement and could greatly accelerate the development of new drugs that may cure patients, eliminating the need for organ transplants altogether.” • Challenges: • Adequate source of expendable cells • Optimization of scaffolds • Creation of bioreactors which simulate the environment of the body and can be scaled-up • Preservation of the product (microcirculation)

3. Where can you get graduate education in these biotech fields? • Funny you should ask? • UC Davis has programs in all of these areas!!!!

4. “New NCI center” Nature May 17, 2001

5. UCD is a Leader in Biology Research Member of the prestigious Association of American Universities (only invited 62 members) Ranked 11th among public universities in the U.S. (US News & World Report-2002) Ranked 6th for graduate programs in biology among US public universities Has nationally ranked programs in: Agriculture & Plant Biology Bioengineering Veterinary Medicine & Animal Science Medicine Food Science & Nutrition Toxicology & Environmental Sciences Evolution and Ecology Microbiology Molecular & Cell Biology . . & more

6. Phyllis Wise, new Dean of the Division of Biological Sciences at UC Davis shares her Vision (Dateline, Feb 1, 2002) Q: Regarding biological sciences, in what areas do you think UC Davis can contribute most substantially to the state and beyond? A: “ Davis hosts the Biotechnology Program (and) the UC-wide Biotechnology Research and Education Program (UCBREP). We are excited about the new genome building and the focus on genomics. The four areas of genomics, proteomics, biotechnology and bioinformatics impinge on every section of the division. And I think the state economy will be enhanced by our ability to contribute.”

7. UC Davis is Tops in Producing PhDs in Biosciences: • Survey of Earned Doctorates in Biosciences (1998-2001). • sources: NSF, NIH, US Dept of Education, NEH, USDA, NASA 2001 1. Johns Hopkins 111 2. Harvard 103 3. UC Davis102 2000 1. University of Wisconsin, Madison 143 2.UC Davis 113 3. UCLA 100 4. Johns Hopkins 92 1999 1. University of Wisconsin, Madison 119 2.UC Davis 118 3. Harvard 112 4. Johns Hopkins 94 5. Cornell 89  1998 1.UC Davis 129 2. University of Wisconsin, Madison 123 3. Harvard 107 Note: UC Davis was number one from 1986-1998. (first survey was in 1986)

8. Our Motto:“Biotechnology: The Tools to Forge a Better Tomorrow” • Central Unit of Office of Research • Founded in 1986 • Administrative home for the DEB & ADPgraduate programs, NSF and NIH Biotechnology Training Grants • Links Academia to Biotechnology Industries & Gov’t agencies • Education Source for Students, Teachers, and Community • Summer Short Courses • “Train the Trainers” (NSF grant) for CC & HS teachers • Advisory committees for many Biotechnology Programs UNIVERSITY UCD Biotechnology Program INDUSTRY & GOVERNMENT Http://www.biotech.ucdavis.edu

9. Designated Emphasis in Biotechnology • The DEB is an inter-graduate group program that allows Ph.D. students to receive and be credited for training in the area of biotechnology and/or bioinformatics. See www.deb.ucdavis.edu • Students come from a wide array of disciplines: Biochemistry, Chemistry, Molecular Biology, Microbiology, Genetics, Chem Engineering, Agriculture and Environmental Chemistry, Statistics, Comparative Pathology, Food Science, Biomedical Engineering, etc. • Mission: to explore biotechnology through seminars and courses and examine the relationship of academia to industry through internships. • This program supplements a student's Ph.D. curriculum. Those completing the DEB program will obtain an official designation on their transcript indicating a qualification in biotechnology.

10. UC Research is a driving force for the growth of Biotech: • New research programs • New research labs • Continued growth in funding • Collaborations with industry • Undergraduate research is highly values • Support for graduate education is a constant goal

11. October 2001 UCBREP Comes to UC Davis University of California Systemwide Biotechnology Research and Education Program (Multi-Campus Research Unit of the Office of the President) Funding & Educational Opportunities! www.ucsystemwidebiotech.ucdavis.edu Dr. Martina Newell-McGloughlin (past director of the UCDavis Biotechnology Program) is the new Director of Biotechnology for all UC campuses. Gussie Curran is Associate Director Co-located in the offices of the Dean of the Division of Biological Sciences with the UC Davis Biotech Program

12. UC Davis has the third-largest invention-property income in the UC system (about $7.3 million in fiscal year 1999), with more than 170 active patents.

13. Free CD ROMS & Video on Biotechhttp://www.nhgri.nih.gov/educationkit/ • Request this multimedia kit which includes a CD-ROM, video, poster and a brochure. On the website, you can view some exciting instructional material with excellent graphics and flash 3D animation on many molecular biology topics including "How to Sequence a Genome". Very useful for teachers and students. • The kit, called The Human Genome Project: Exploring our Molecular Selves, includes: a CD-ROM with seven varied segments * an award-winning video documentary, The Secret of Our Lives * a commemorative poster * an informational brochure, Genetics: The Future of Medicine, Basic Genetics- a glossary of genetic terms, The Human Genome Project Exploring Our Molecular Selves, Goals of the Human Genome Project, Unlocking the Mysteries of Health and Disease: Gene Discovery Understanding Biological Function, Genetic Testing and Gene-based Medicine, Development of Genetic Medicine "

14. Questions???? • Please contact me at: email: jakjelstrom@ucdavis.edu tel: 530-752-8228 The Future looks Bright for Life Scientists!