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Cas9 protein plays a vital role in the immunological defense of certain bacteria against DNA viruses and plasmids and which is heavily utilized in genetic engineering applications. PNA Bio offers the quality cas9 protein for research purposes.<br>
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Cas9 Protein with NLS Cas9 protein, in complex with guide RNA, offers benefit for CRISPR/Cas9 technology over plasmid or mRNA transfection. The biggest advantage is that by incubating Cas9 protein and sgRNA briefly, you can form an RNP complex that is ready to work in vivo as soon as it is delivered into the cells or an embryo. Cas9 protein is short lived (about 24 hours of half-life in cells), thus minimizes the off target effects and mosaicism. CRISPR/CAS9 PRODUCTS
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