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Endocrine Slide Show

Endocrine Slide Show. Question 1. Name two clinical signs in the photo Likely diagnosis Name another sign of this condition. Question 1. Exopthalmos & Goitre Grave’s Disease Pretibial myxoedema (see photo) Lid lag. Question 2. Diagnosis?

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Endocrine Slide Show

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  1. Endocrine Slide Show

  2. Question 1 • Name two clinical signs in the photo • Likely diagnosis • Name another sign of this condition

  3. Question 1 • Exopthalmos& Goitre • Grave’s Disease • Pretibial myxoedema (see photo)Lid lag

  4. Question 2 • Diagnosis? • What would the blood abnormalities be if this person wasn’t dead? • What other investigations might you do?

  5. Question 2 • Paget’s • High Alk PhosNormal Calcium (may be slightly raised if ++ patient immobility) • Urinary hydroxyproline (raised in Paget’s)X-rays (localised bone elargement, sclerotic bones)DEXA scan (high bone turnover in spine, skull & long bones)

  6. Question 3 • Diagnosis? • Name 4 features visible in this image

  7. Question 3 • BACKGROUND diabetic retinopathy • See diagram

  8. Question 4 • Diagnosis? • Expected blood results? • Management?

  9. Question 4 • Hypothyroidism/a bit fat • TSH >5mu/L & T4 < 70mmol/L (1°) or normal TSH (2°) • Levothyroxine

  10. Question 5 • Diagnosis? • Expected test results? • Management?

  11. Question 5 • Cushing’s Syndrome (or too many pies) • Remove tumour (if Cushing’s disease)Stop steroids (if iatrogenic)

  12. Question 6 • What’s the diagnosis? • JFK had fatigue, wt loss, weakness, depression, N&V, diarrhoea and fainting • How would you confirm your diagnosis?

  13. Question 6 • Addison’s • Low Na, High K, Low Glucose, Low Cortisol, High Ca, eosinophilia, anaemia

  14. Question 7 • Spot diagnosis? • Causes?

  15. Question 7 • Hirsutism • FamilialIdiopathicPCOSOvarian CaCAHCushing’sDrugs (steroids)

  16. Calcium – high Alk Phos – high Phosphate – high 25 OH vitamin D – low Diagnosis? Question 8

  17. Question 8 • Osteomalacia

  18. K+ - high Na+ - slightly high Metabolic alkalosis Low renin High aldosterone Diagnosis? Question 9

  19. K+ - high Na+ - slightly high Metabolic alkalosis Low renin High aldosterone Conn’s syndrome Question 9

  20. Question 10 • Diagnosis? • Management?

  21. Question 10 • Paget’s • Simple analgesia & bisphosphonates

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