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GENETICS OF VIRUSES

GENETICS OF VIRUSES. The Basics. Compare the size! Two basic components: A diverse genome ssDNA dsDNA (Smallpox) ssRNA (Measles) dsRNA Capsid/Envelope. Viral Structure. Obligate Intracellular Parasites?. Host range varies with virus Swine flu vs. smallpox Tissue specific

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GENETICS OF VIRUSES

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  1. GENETICS OF VIRUSES

  2. The Basics • Compare the size! • Two basic components: • A diverse genome • ssDNA • dsDNA (Smallpox) • ssRNA (Measles) • dsRNA • Capsid/Envelope

  3. Viral Structure

  4. Obligate Intracellular Parasites? • Host range varies with virus • Swine flu vs. smallpox • Tissue specific • Cold virus to AIDS virus • What determines the limits to the host range?

  5. Lytic Cycle • The “virulent” phage • Why are bacteria not extinct?

  6. Lysogenic Cycle • The “temperate” phage • How is the prophage involved?

  7. Viral Envelopes • Describe the steps: • How does Herpes virus differ?

  8. Retrovirus • HIV

  9. Vaccines • How do they work? • Why can’t viruses be treated with antibiotics? • Eradication of viral diseases…how is this possible? • Smallpox (1976)

  10. Emerging Viruses • Why are some example? • Why are they typically RNA viruses? • Why do they spread?

  11. Plant Viruses

  12. Viroids & Prions

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