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DISSERTATION TOPICS COVERED IN THE MOLECULAR AND CELLULAR BASICS OF CANCER AND DEVELOPMENT OF TARGET-SPECIFIC THERAPEUTICS-CANCER/ONCOLOGY An Academic presentationby Dr.NancyAgens,Head,TechnicalOperations,Pubrica Group: www.pubrica.com Email:sales@pubrica.com
Today'sDiscussion Outline InBrief Introduction Topics Covered in Molecular Basics of Cancer Conclusion
InBrief Researching cancer and its therapeutics is an important tool for cancer studies and medical writingservices. The important topics to be covered while writing a thesis for cancer and its therapeutics are discussed in scientific medical writing. Pubrica is here to help with the easyscientific medical writing about cancer researchand itstherapeutics.
Introduction Cancer is one of the life-threatening diseases, responsible for the mortality rate of 0.13% ofthe world'spopulation. It is essential to perform research in the fieldof cancer to overcome the emergency demand to control the death rate ofcancer. The cancer researchmainly has done to analyze the risk, to know the type of cancer, to studyabout the therapeutics etc with the helpofmedical writingsolutions. Contd..
The first and foremost essential knowledge to perform cancer research for a scientist is to know about the cellular basics of cancerdevelopment. Once after attaining knowledge, the researcher should submit athesis about hiswork. Here are a few molecular and cellular basics aboutcancer/oncology.
Topics Coveredin Molecular Basics of Cancer Stability of acell Instablegene Oncogenesis Suppressor genes fortumour The growth phase oftumour Angiogenesis Metastasis and modelsystems Therapeutics Contd..
1.Stability of aCell The most common cause of cancer is an undefinedmass of cellgrowth. It is essential to check the stability of aDNA inside thecell during the replication, transcription andtranslation. Also, the DNA polymerase enzyme is the reason forthe correct nucleotideactivity. The above-mentioned are the basics of cellfunctioning. Whenever there is a problem in cell functioning, it maylead to celldamage. Contd..
2. InstableGene The cell damage can lead to geneticinstability. This process will change the structure of DNAand causes mutations andcancer. It will lead to the carcinogens to easily rupture the cellular metabolicprocess. This unstable gene leads tooncogenesis. Contd..
3.Oncogenesis Oncogenesis is the process of transformation of normal cells to cancercells. Activation ofoncogene Cell division takes place in an unmanageablemanner Contd..
4. Tumour Suppressor Genes Thetumour suppressorgenes stop functioningwith inactivation of two alleles duringoncogenesis. It will mislead the cell signallingpathways. For a non-cancerous cell, a TSG inhibit thegrowth ofcancer. Hence it is called as the caretakers of thebody. Contd..
5. GrowthPhase ofTumour The forementioned oncogene and TSG function will leadto decisive variations in cellulargrowth. This tumour cells will develop into cancer cells byshifting the equilibrium between apoptosis and proliferation of excessive cellgrowth. There will be a disturbance in the cell cyclepathways during this growthphase. Contd..
6.Angiogenesis The tumour cells need oxygen and nutrients supply from theblood. It will be obtained by passing the chemical signals to the bloodvessels. However, there are several anti-angiogenesis drugs to inhibit thisprocess. Contd..
7.Metastasis and Model Systems Metastasis is the process, where cancer cells exploreinto foreign sites, leaving their primesite. In the next stage of metastasis, the cancer cells enterinto the lymphatic organs and bloodstream, that leads to cancerdeath. There are certain model systems to study the characterization of a phenotype and genotype. Allthe models should explain usingmedical writinghelp. Contd..
8.Therapeutics The need for cancer studies is mainly toaccess treatment. Scientists have developed many therapeutic agents for cancer studiesbut it is still in vain to cure acertain type of cancer especially bloodcancer. The cancer treatment will have both theadvantages and disadvantages depending upon the body condition of apatient. There is no particular treatment available forcancer. Contd..
Out of all chemotherapy and drug treatment is the most commontherapeutics for cancertreatment. Drug treatment is less toxiccomparatively. The above-mentioned passages are the topics to be discussed while doinga dissertation in cancerstudies. It will ample information about the entry of cancer cells and the phases ofcancer at a molecular level in ourbody. Medical writingsolutionsare there to complete the dissertation of topics ofbasic cellular level ofcancer.
Conclusion Pubrica has given the details for the basic levelcancer study researchworks. It will be helpful for the researchers to develop avaccine or medicine that inhibitscancer. The cancer study dissertation can be done with thehelp ofmedical writingsolutionsandservices. These basics will also help to do evaluations infuture cancerstudies. This article is fully checked with plagiarismcorrection and will be analysed by scientific writingcompanies.
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