What is a Systematic Review? - Pubrica

1. WHAT IS A SYSTEMATIC REVIEW An Academic presentationby Dr. Nancy Agens, Head, Technical Operations, Pubrica Group: www.pubrica.com Email:sales@pubrica.com

2. Outline Today'sDiscussion Inbrief Introduction What makes an Excellent Systematic Review Different types ofReviews Differences between Systematic and Literature Reviews Conclusion

3. InBrief A systematic review is a secondary research as it requires a careful analysis of the quality, quantity, and consistency of research findings. Systematic reviewsformulate research questions that are specifically targeted and designed to provide a complete summary of the issuebased on evidence. The methodology used in systematic reviews is specific and precise, which intends to minimize bias by increasing the reliability of the drawnconclusion.

4. A systematic reviewis a process of identifying comprehensive studies for a research specific question through evaluating the methods of the study, summarizing the results, presenting key findings and identifying reasons for produced results across thestudy. In a systematic review, the compiled information tends to be explicit and more transparent using reproduciblemethods. The produced results of a systematic review can be summarized either in text orgraphic form, and it depends upon the nature of the primarydata. The PRISMA, provides a set of regulations on how to report a systematicreview. Introduction

5. A good systematic reviewwillinclude, A focused question Inclusion/exclusion criteria Searchstrategy Studyselection Assess the quality ofstudies Synthesize studyresults What makes an Excellent SystematicReview? Analysis andlimitations Contd..

6. a systematic review is a research method used to address a specific research question and formulating a well-constructed research question is essential for a successfulreview. INCLUSION/EXCLUSIONCRITERIA It studies the writers included or excluded and thereason. SEARCHSTRATEGY The reviewer must explain the methods used for finding relevant studies which include published and unpublished clinical trial reports, online database search, as well as approaching experts in finding unpublisheddata. Contd.. 1. FOCUSEDQUESTION

7. STUDYSELECTION Need to identify suitable study criteria and collect relevant data for conducting a systematicreview. ASSESS THE QUALITY OFSTUDIES It helps in identifying the risk of bias in secondaryresearch. SYNTHESIZE STUDYRESULTS Upon similarity on the included data, the author must determine the effectiveness of an intervention usingmeta-analysis. ANALYSIS ANDLIMITATIONS The review should discuss the addressed area of study, the findings, and how the review results change the existinglimitations.

8. There are many types of reviews addressing questions of effectiveness, questions about the prevalence of diagnostic accuracy, and prognosis. Different types of reviewsinclude, LiteratureReview Meta-analysis Rapid review Scoping review Systematicreview Systematizedreview Umbrellareview Different types ofReviews:

9. SystematicReview LiteratureReview Differences between Systematic and LiteratureReviews It describes an overview and not based on a singlequestion. It has noprotocol. No such objectives will be identified. Search strategy will not be mentioned. Notdescribed Extracting relevant information is not specific to a singlequestion Mainly focused on onequestion. It follows peer review protocol or plan. Study-specific objectives are identified. A systematic search will be conducted. Clear andexplicit. Research question specific information extraction.

10. Conclusion In summary, a systematic reviewis a search of all sources of evidence for relevant studies or on research question specificstudy. Predetermined reproducible criteria to screen for eligibility and relevanceassessment of titles and the abstracts will befollowed. Each study will then be assessed in terms of methodological quality, and finally, the evidence issynthesized.

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