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Risk Factors and Outcomes of Donor Lenticule Dislocation Following DSEK

Risk Factors and Outcomes of Donor Lenticule Dislocation Following DSEK. Pravin K Vaddavalli MD, Suntia Chaurasia MD, Muralidhar Ramappa MD, Prashant Garg MD, Virender S Sangwan MD Cornea & anterior segment service LV Prasad Eye Institute Hyderabad India.

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Risk Factors and Outcomes of Donor Lenticule Dislocation Following DSEK

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  1. Risk Factors and Outcomes of Donor Lenticule Dislocation Following DSEK Pravin K Vaddavalli MD, SuntiaChaurasia MD, MuralidharRamappa MD, PrashantGarg MD, Virender S Sangwan MD Cornea & anterior segment service LV Prasad Eye Institute Hyderabad India None of the authors have any financial interest in the subject matter of the presentation

  2. Purpose: To review the clinical profile of graft detachment following Descemet’s stripping endothelia keratoplasty (DSEK) and analyze the outcomes of re-bubbling for graft detachment. Design: Retrospective case review

  3. Methods • 309 eyes underwent DSEK from January 2009 to February 2010 • 27 eyes (8.7%) developed graft detachment • 20 males and 7 females; age range 23 to 82 years • Graft detachment: complete/total if there was no area of contact between the lenticule and the host posterior stroma • partial/incomplete if there was some extent of apposition of the graft with the posterior stroma • re-bubbling with air with or without repositioning if complete dislocation, partial detachment with communication with anterior chamber and significant decentration

  4. Surgical parameters

  5. Outcomes

  6. Clinical and surgical data of patients with Persistent detachment after first Rebubbling

  7. Risk factors for persistent graft detachment after unsuccessful first re-bubbling intervention

  8. Conclusions • Graft dislocation rate 8.7%, all noted within the first week of surgery • Graft detachment may be anticipated more commonly in aphakic and vitrectomised eyes • additional vitrectomy at the time of surgery is a significant risk factor for persistent graft detachment

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