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Molecular View of Anatomy. Ya -Min Chi. 1S0V.
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Molecular View of Anatomy Ya-Min Chi
1S0V Tyr 639 helps RNA polymerase to determine ribose structure and deoxyribose structure. Its stabilized by magnesium ion. The Tyr 639 helps RNA polymerase to read the DNA template strand for transcription. The hydroxyl group on the Tyr interact with the OH group of substrate ribose. This is how Tyr help determine ribose and deoxyriboe.
Hemoglobin (2HHB)1.74Å vsMyoglobin (1MBO) 1.6Å Sulfate ion This image is the superposition of myoglobin (purple) with chain A of hemoglobin (white). In general, the backbone structure of the two structures are really similar. However, at the end of the structure, myoglobin is longer. This might prevent myoglobin from forming a stable tetramer with itself.
The yellow surfaces show the hydrophobic region of the two structures. From this, we see that hemoglobin has more hydrophobic region on the surface than myoglobin has. Thus, hemoglobin form a tetramer to reduce the surface of hydrophobic interaction.