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Structure of Ad-TRE. 31,476 bp. Capacity ~5.1 Kbp. ITR. ITR. Adenovirus serotype 5. E1 deletion replaced by:. E3 deletion. min CMV. Gene of Interest. b -globin. pA. 7 tetO. min CMV = CMV TATAA box and 5’ UTR.
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Structure of Ad-TRE 31,476 bp Capacity ~5.1 Kbp ITR ITR Adenovirus serotype 5 E1 deletion replaced by: E3 deletion minCMV Gene of Interest b-globin pA 7 tetO minCMV = CMV TATAA box and 5’ UTR