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URM and IMRAD format. Vancouver group. 1978, Vancouver, Canada Uniform submission Make life easier for authors No rejection on grounds of style. Uniform Requirements for Manuscripts Manuscript Preparation Preparing a Manuscipt for Submission to Biomedical Journals
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Vancouver group • 1978, Vancouver, Canada • Uniform submission • Make life easier for authors • No rejection on grounds of style
Uniform Requirements for Manuscripts • Manuscript Preparation • Preparing a Manuscipt for Submission to Biomedical Journals • Sending the Manuscript to the Journal • References • Print References Cited in this Document • Other Sources of Information Related to Biomedical Journals
Parts of an essay Beginning Main Body End
Sir Bradford Hill’s Questions • Why did you start? • What did you do? • What did you find? and • What does it all mean?
Parts of a paper: IMRAD I Introduction M Methods R Results a and D Discussion
Sir Bradford Hill’s Questions I Introduction Why did you start? M Methods What did you do? R Results What did you find? A and D Discussion What does it all mean?
Introduction Why did you start? Readers’ expectations • Sufficient background information • Understand and evaluate the results • Without referring to previous publications Concise, adequate Not a review
Introduction • Review pertinent literature • Define lacunae in current knowledge • Provide rationale for your study • What gap in knowledge did you try to fill? • What controversy did you try to resolve? • State the aim of the study
Introduction • Brief, clear, to the point • Written in present tense • May state the study group, study design and methods used
Introduction • Key references: to support background information • Refer to • your previous preliminary work • your own closely related papers • Define any specialized terms, definitions or abbreviations you intend to use
Example We wish to suggest a structure for the salt of deoxyribose nucleic acid (D.N.A.). This structure has novel features which are of considerable biological importance. Watson JD, Crick FHC. A structure for deoxyribose nucleic acid. Nature 1953; 171: 737-8.
Methods What did you do?
Methods • What all was done? • How was it done? • When was it done? • Who did it ? • How were the results analyzed? • Did you have ethical clearance to do so?
Methods • Present methods in chronological order • Subheadings should match those in results ‘internal consistency’ • In past tense • Be precise
Methods: checklist • Does it describe • What questions was being asked? • What was being tested? • How reliable was the measurement? • Were the parameters recorded and analyzed correctly? • Would a reader be able to repeat the same experiment?
Results What did you find? Answers
Results: Before writing • Collate data • Prepare master tables • Re-check accuracy • Analyse • List all the findings • Identify the important ones
Results: The components • Text Story • Tables Meat • Figures Drama
Results • Results of all experiments in natural order in subsections similar to methods • Do not duplicate information text, tables, figures • Statistical analysis
Results • Should not include • Any methods • Data for which methods are not included • Interpretation of data • References
Results: Tables Table I. Parts of a table Footnote: BODY
Results: Table or figure • Prefer tables • Use figures only for illustrative • Bar, histogram, pie: ? table Difference in written and oral communication
Results: Text or Tables • Number of items • Few variables: Text • Many variables: Table
Intraperitoneal inoculation of 1 X 106 DLA cells (day 0) Treatment (d 1,2,3) Observation 0 1 2 3 4 30 Days Group 1 Vehicle Group 2 Total alkaloid fraction (5 mg/Kg/d) Group 3 Total alkaloid fraction (10 mg/Kg/d) Group 4 Total alkaloid fraction (20 mg/Kg/d) Group 5 Methotrexate (3.4 mg/Kg/d) (Positive control) Figure: in place of text Study design
Summary • URM • IMRAD • Introduction • Methods • Results and • Discussion