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Toxoplasma gondii

Toxoplasma gondii. http://www.cdfound.to.it/html/tg10.htm. Toxoplasma gondii. Tachyzoites http://www.stanford.edu/group/parasites/ParaSites2006/Toxoplasmosis/index.html. Protozoan parasite Coccidia Common 20 – 60% cats 70% humans Causes toxoplasmosis. Location and Hosts.

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Toxoplasma gondii

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  1. Toxoplasmagondii http://www.cdfound.to.it/html/tg10.htm

  2. Toxoplasmagondii Tachyzoites http://www.stanford.edu/group/parasites/ParaSites2006/Toxoplasmosis/index.html • Protozoan parasite • Coccidia • Common • 20 – 60% cats • 70% humans • Causes toxoplasmosis

  3. Location and Hosts http://www.innocentenglish.com/wp/wp-content/uploads/2008/01/cats-kitten-sink.jpg • Every country! • High in: • France • Central America • Definitive Host • Intermediate Hosts

  4. Sites of Infection Foodborne Zoonotic Congenital Transmission

  5. Pathogenesis/clinical signs Healthy People Acute Infections Subacute Infections Chronic Infections Immunocompromised Patients Pregnant Mothers Toxoplasmosis

  6. Diagnosis • Biopsy • Mice inoculation • Serological testing • Antibodies • IgG, IgM • PCR of amniotic fluid • CT scan, MRI

  7. Treatment • Not necessary if healthy • Necessary in: • Pregnant women • Immunocompromised • Ocular diseases • Severely ill • Medications: • Spiramycin • Pyrimethamine plus Sulfadiazine • Clindamycin • Antimalarial drugs

  8. Control Avoid litter boxes and proximity with cats Avoid undercooked meats Wash hands Wash fruits and vegetables Avoid untreated water Control rodent/intermediate host populations Do not allow cats to hunt or roam

  9. References http://www.healthgene.com/vet/a112.asp http://www.vet.cornell.edu/fhc/brochures/toxo.html http://www.essortment.com/all/whatistoxoplas_rhjv.htm http://www.marvistavet.com/html/body_coccidia.html http://www.omafra.gov.on.ca/english/livestock/swine/facts/04-055f1.jpg http://www.dpd.cdc.gov/dpdx/HTML/Toxoplasmosis.htm https://health.google.com/health/ref/Toxoplasmosis CDC. Toxoplasmosis. Division of Parasitic Diseases and the National Center for Zoonotic, Vector-Borne, and Enteric Diseases. 2008. Accessed Jan 2010. http://www.cdc.gov/toxoplasmosis/epi.htm Hokelek, Murat, MD, PhD. Toxoplasmosis. Dept of Clinical Microbiology, OndokuzMayis University Medical School, Turkey. 2009. Accessed Jan 2010. http://emedicine.medscape.com/article/229969 Schmidt, G. and Roberts, L. Foundations of Parasitology, 8th ed. p134-139. McGraw Hill Companies Inc, 2009.

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