Medical Student Research Program Orientation

1. Medical Student Research Program Orientation August 10, 2011 Ginny L. Bumgardner MD PhD FACS Associate Dean for Research Education

2. Introductions • Ginny L. Bumgardner, MD, PhD • Associate Dean of Research Education • Director of Medical Student Research • Director of Masters of Medical Science • PI of HHMI Med-into-Grad • Kelly Dillon, MA • Program Coordinator Medical Student Research • Benjamin Wendt • Med II • Landacre President 2011-2012

3. Introduction to Medical Student Research Program The Office of Research Education's Medical Student Research Program aims to promote awareness of research opportunities and facilitate research success for OSU medical students. • Provide tips on how to find a faculty research advisor and current research opportunities. • Serve as a resource for information about research, research mentors and research funding for medical students. • Facilitate application to internal and extramural funding opportunities for eligible Medical Student Research projects. • Publicize news, research accomplishments, presentations, and publications by OSU medical students.

4. Biomedical Research Medicine What is Research Education? • Research Education is training that incorporates activities involved in the process of • Discovery through Critical Thinking, Innovation & Experimentation • Communication of New Knowledge • Application of New Knowledge to enhance Patient Care • Evaluation of Outcomes in Humans

5. Office of Research Education • Undergraduates • Graduate Students • Postdoctoral Fellows & Researchers • Medical Scientist Program • Medical Students • Residents & Fellows

6. Relevance to your Medical Education 6

7. Relevance of Research Education to Physician TrainingProblem Solving Health------Disease-----Intervention-----Outcome & Assessment • Ask Important Health Related Questions • Develop an Action Plan (Research) to Answer the Question • Action • Evaluate the Results of the Action Plan • Communicate the Conclusions

8. Medical Student Research Program Goals • Training in Biomedical Research • Formulating Research Questions • Team Operations • Research Experimental Skills • Research Presentation Skills • Criteria & Competition for Funding

9. Medical Student Research ExperienceValue • First Hand Experience in Biomedical Discovery • Depth of Knowledge in a Particular Field • Develop Research Skills • Influence on Your Career Opportunities • Advance the Future of Medicine • Influence Institutional Reputation

10. Why Research?In Medical Students’ Own Words • “Although research may not be for everyone, the ability to locate and interpret journal articles is a key skill gained from performing research that will be useful as a practicing physician and will ultimately be a great benefit to their patients. • “I believe that involvement in scientific research during medical school equips me with both the intense skeptical inquiry of a research scientist and the clinical experience necessary to focus my research efforts toward enhancing patient care.” • “With the time that I devote to the research lab, I imagine that my time is devoted to a thousand unnamed patients. These are patients that I will never know and who will never know me, but their foothold rests in my efforts to take on an unanswered question, or a treatment that hasn’t been tried.”

11. Medical Student Research Achievements Institutional Reputation

12. Research affords you advanced opportunities, experiences 12

13. 2011 Research Day Travel Award WinnersMedical Student Researchers (N=13) • Tyler Oostra, “Id Protein Overexpression Affects Cell Proliferation and Cell Signaling Proteins in Medulloblastoma,” Mentor: Christopher Pierson • Benjamin Wendt, “Qualitative and quantitative radiological anatomical variation of the posterior clinoid process,” Mentor: Mario Ammirati • Manoj Rajagopal, “Efficacy of Core Decompression as Treatment for Avascular Necrosis of the Hip: A Systematic Review,” Mentor: Thomas Ellis • Gregory Sams, “A novel mouse model for cutaneous T-cell lymphoma reveals a role for IL-15,” Mentor: Michael Caliguiri • Bethany Brisbin, “Id Proteins Enhance Cell Proliferation and Contribute to the Malignant Phenotype of Human Medulloblastoma,” Mentor: Christopher Pierson • Megan Yanik, “Identification of Pediatric Overweight and Obesity by Primary Care Providers,” Mentor: Sarah O'Brien

16. Points of Pride • Presentations • Ben Abramowitz, 2009 Roessler recipient and Landacre Inductee, "Swelling Analysis of Biomechanical Properties in the Post-LASIK Cornea," National Association for Research in Vision and Ophthalmology National Conference, May 2011 • Lisa Caronia, 2010 Roessler recipient and Landacre Inductee, “Developing Prognostic Criteria for Malignant Neuroendocrine Tumors" at the Meeting of the North American Neuorendocrine Tumor Symposium, October, 2010. • Publications • Elaine Binkley, 2008 Roessler recipient and Landacre Inductee, “Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4+ T cells from patients with GI malignancy" in the Journal of Cancer Immunology and Immunotherapy. • Lisa Caronia, 2010 Roessler recipient, "A Genetic Basis for Functional Hypothalamic Amenorrhea," published in The New England Journal of Medicine in January, 2011.

17. Points of Pride

18. How do I find out about research and funding opportunities? 18

19. Internal and External Medical StudentResearch Funding Opportunities • External Fellowships • HHMI • NIH • AOA • Foundations (AHA, ADA, AAS, …) • Sarnoff • Doris Duke • COM Competitive (Limited #) Scholarships • Samuel J. Roessler Memorial Scholarship • New in 2008, Watts Scholarship-Patient Centered Research Ethics • New in 2009, Barnes & Bennett Scholarship • Support for 1 year LOA at OSU • New in 2010, OSU Pelotonia: cancer focus • New in 2008, OSU CCTS: degree

21. 2011 Medical Student Research Scholarship Application Information - Categorization 21

22. 2011 MDSRSA Mentor Departments Allied Medical Professions Ambulatory Pediatrics Anatomy/BMI Anesthesiology Biomedical Engineering Cardiothoracic Surgery & Cardiovascular Medicine Center for Molecular and Human Genetics Critical Care, Trauma and Burn Family Medicine Hematology/ Internal Medicine Infectious Disease Internal Medicine Molecular and Cellular Biochemistry MVIMG Neurology, Neurosurgery or Neuroscience Opthalmology Orthopedics Otolaryngology Pathology Pediatrics & Pediatric Surgery Physical and Rehabilitative Medicine Radiation Oncology Radiology Surgery Urology 22

23. Information and Help SessionsBecome an active participant in your own future! • 2011-2012 Medical Student Research Program Calendar of Events • Landacre Meetings and Events • One-on-one assistance with prestigious national fellowship applications (e.g., HHMI, Sarnoff, Doris Duke, AOA) • Know your deadlines, know your limits

24. Resources Available • Landacre Executive Board • Benjamin Wendt, President • Eliza Beal, Vice President • Landacre Interest Group • Medical Student Research Program Office • 1170 Graves Hall • research.education@osumc.edu • Medical Student Research Program Website • http://medicine.osu.edu/go/mdsr • MD2B Newsletters (email)

25. Landacre Honor Society

26. 2011-2012 Landacre Honor Society • Benjamin Wendt, President • Eliza Beal, Vice President • Rohit Mital, Treasurer • Joel Palko, Secretary • Nicholas Nowacki, Officer • Josephy Meyerson, Officer